Results 121 to 130 of about 1,832,123 (358)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Study on Early Warning Methods for Shipping Input Risks Under Consideration of Public Health Events

open access: yesApplied Sciences
The rapid expansion of economic globalization and trade has led to a sharp increase in the shipping investment risks currently faced by cities around the world.
Zhanxin Ma   +3 more
doaj   +1 more source

THE “DARK” AND THE “BRIGHT” SIDES OF POWER IN SUPPLY CHAIN NETWORKS [PDF]

open access: yes
One of the prerequisites for a supply chain network is the existence of a focal company, which possesses power to coordinate the network in order to realize its strategic objectives.
Belaya, Vera, Hanf, Jon Henrich
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

GResilient index to assess the greenness and resilience of the automotive supply chain [PDF]

open access: yes
Purpose: The purpose of this paper is to suggest an Index entitled GResilient Index to assess the greenness and resilience of the automotive companies and corresponding supply chain. Design/methodology/approach: An integrated assessment model is proposed
Azevedo, Susana G.   +3 more
core  

Pengukuran Kinerja Supply Chain Berdasarkan Proses Inti Pada Supply Chain Operation Reference (Scor) (Studi Kasus Pada PT Arthawenasakti Gemilang Malang) [PDF]

open access: yes, 2014
Supply chain memiliki peranan yang penting dalam proses aliran material mulai dari pasokan bahan baku oleh supplier sampai produk jadi ke tangan konsumen.
Maulidiya, N. S. (Nurus)   +2 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Green House Gas Emission Analysis in the Food Processing Industry: A Case Study of MSME in South India

open access: yesEngineering Proceedings
Rising carbon emissions are worsening global climatic conditions, posing a grave threat to the environment. Analysing and reducing carbon footprints are vital for combating climate change.
Gangavarapu Chenchu Chythanya Krishna   +5 more
doaj   +1 more source

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