Results 121 to 130 of about 1,809,313 (357)

Towards a business model for sustainable supply chain management [PDF]

, 2013
Designers make decisions that ultimately impact on both the economic, environmental and social performance of the products and process, and many of these costs and impacts occur across the supply chain.
Ball, Peter D., Pimenta, Handson
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Liner Schedule Design under Port Congestion: A Container Handling Efficiency Selection Mechanism

Journal of Marine Science and Engineering
Port congestion significantly impacts the reliability of container ship schedules. However, the existing research often treats vessel time in port as a random variable, failing to systematically consider the complex impact of port congestion on ship ...
Haibin Qu, Xudong Wang, Lingpeng Meng, Chuanfeng Han   +3 more
doaj   +1 more source

Research on the Intelligent Development of Rural Financial Supply Chain under the Background of Internet of Things [PDF]

, 2022
Xiang Sui
openalex   +1 more source

Strategic, tactical decisions and information in Rapid Manufacturing supply chain [PDF]

, 2011
The efficiency and agility of its supply chain is vital to the commercial success of any product. Sharing strategic and tactical information effectively within the supply chain is often a key factor in achieving this goal. This paper proposes a framework
Earl, C. F., Eckert, C. M., Hasan, S.
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Green House Gas Emission Analysis in the Food Processing Industry: A Case Study of MSME in South India

Engineering Proceedings
Rising carbon emissions are worsening global climatic conditions, posing a grave threat to the environment. Analysing and reducing carbon footprints are vital for combating climate change.
Gangavarapu Chenchu Chythanya Krishna, Chelakari Ravi Karthika, Chindukuru Sushwanth, Guggila Hema Gopi Chand, Firoz Nasirudeen, Vinay V. Panicker   +5 more
doaj   +1 more source

Mastering supply chain risks [PDF]

, 2012
Borut Jereb, Tina Cvahte, Bojan Rosi
openalex   +1 more source

Revisiting the Academic-practitioner Model: Searching for a Fit Between Classroom Content and the Need in the Field - A Supply Chain Perspective

, 2023
Lathan Craig Austin, Shalom Charles Malka   +1 more
openalex   +1 more source