Results 161 to 170 of about 5,758,776 (359)

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

AI Applications in Supply Chain Management: A Survey

Applied Sciences
The advent of Industry 4.0 and the integration of Artificial Intelligence (AI) is transforming supply chain management (SCM), improving efficiency, resilience and strategic decision-making capabilities.
Adamos Daios, Nikolaos Kladovasilakis, Athanasios Kelemis, Ioannis Kostavelis   +3 more
doaj   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

The mediating role of service innovation in the relationship between customer orientation and patient satisfaction

BMC Health Services Research
Introduction Declining patient satisfaction signals a pressing challenge in healthcare service quality; however, the role of service innovation in addressing this issue remains underexplored.
Joseph G. Yeboah, Kojo Tei Amponsah
doaj   +1 more source

INNOVATION THROUGH (INTERNATIONAL) FOOD SUPPLY CHAIN DEVELOPMENT: A RESEARCH AGENDA [PDF]

This paper presents a research agenda on innovation through (international) food supply chains and networks in developing countries. It derives major topics from a multi-perspective view on international food chains (economic, technology, social/legal ...
Beulens, Adriaan J.M., Hagen, James M., Omta, S.W.F. (Onno), Trienekens, Jacques H.   +3 more
core   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Green Supply Chain Optimization Based on Two-Stage Heuristic Algorithm [PDF]

Chunrui Lei, Heng Zhang, Xingyou Yan, Qiang Miao   +3 more
openalex   +1 more source

COVID-19 as a trigger for dynamic capability development and supply chain resilience improvement

, 2021
Anni‐Kaisa Kähkönen, Pietro Evangelista, Jukka Hallikas, Mika Immonen, Katrina Lintukangas   +4 more
openalex   +1 more source