Results 161 to 170 of about 1,809,313 (357)
Coordination in a two-stage capacitated supply chain with multiple suppliers
, 2011 Peral Toktaş-Palut, Füsun Ülengin
openalex +2 more sources
The Logistic Principles for Fast Flexible Strategy Design of the Company in Crisis Time [PDF]
The article deals with design of the logistic principles enabling an enterprise to create a strategy flexible in terms of business and marketing and stable and steady in terms of manufacturing. In order to create a strategy model the following principles
Dusan Malindzak +2 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
BMC Health Services ResearchIntroduction Declining patient satisfaction signals a pressing challenge in healthcare service quality; however, the role of service innovation in addressing this issue remains underexplored.
Joseph G. Yeboah, Kojo Tei Amponsah
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Supply Chain Management Overview: A Global Team Effort [PDF]
Supply chains have eliminated U.S.
Cliff Welborn
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Anomaly Detection in Blockchain-enabled Supply Chain: An Ontological Approach [PDF]
, 2021 Tahani Hussein Abu Musa +1 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source