Results 171 to 180 of about 1,832,123 (358)

Market-Driven Management and Global Supply Chain [PDF]

Globalization and over-supply have pushed companies to face new competitive challenges. In such a competitive space, a new approach in managing the supply chains and the consequent optimization of material flows and intangible assets plays a crucial role
Lorenzo Petretto, Monica Faraoni
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Enabling Sustainable Manufacturing Through AI-Optimized Supply Chains

, 2022
Raviteja Meda, V Kommaragiri, B Preethish Nanan, V Annapareddy, A Gadi, S Kalisetty, V Pamisetty, A Dodda, J Singireddy, K Challa, S Paleti, V Komaragiri, A Pamisetty, H Sriram, M Malempati, S Challa, S Mashetty, S Mashetty, S Motamary, S Kannan, S Suura, S Nuka, V Annapareddy, H Koppolu, S Kannan, R Meda, V Annapareddy, B Preethish Nanan, V Kommaragiri, A Gadi, S Kalisetty, Phanish Lakkarasu, P Kaulwar, M Malempati, M Recharla, S Chitta, Lahari Pandiri, S Paleti, J Burugulla, L Pandiri, V Pamisetty, K Challa, J Singireddy, S Paleti, J Singireddy, A Dodda, J Burugulla, K Challa, H Sriram, H Koppolu, Chaitran Chakilam, H Sriram, B Adusupalli, M Malempati, Avinash Pamisetty, A Gadi, S Kannan, B Nanan, V Komaragiri, S Singireddy, A Dodda, A Gadi, A Pamisetty, B Adusupalli, Dwaraka Nath, Kummari, B Adusupalli, S Singireddy, H Sriram, P Kaulwar, M Malempati, Karthik Chava, K Challa, V Pamisetty, L Pandiri, V Annapareddy, H Sriram, P Kaulwar, B Nandan, S Chitta, Raviteja Meda, S Rao Suura, Vamsee Pamisetty, Lahari Pandiri, Sneha Singireddy, Narasareddy Venkata, Harish Annapareddy, Kumar Sriram, Someshwar Mashetty, Srinivasa Rao, Challa, S Paleti, V Pamisetty, V Kommaragiri, A Gadi, S Kannan, B Preethish Nanan, V Annapareddy, Venkata Bhardwaj, Komaragiri   +99 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Designing Profitable and Responsive Supply Chains under Uncertainty

, 2019
Amir Azaron, Uday Venkatadri, Alireza Farhang Doost   +2 more
openalex   +1 more source

Optimization of warehousing and transportation costs, in a multi-product multi-level supply chain system, under a stochastic demand [PDF]

, 2010
Kawtar Tikito, Saïd Achchab, Youssef Benadada, Rachid Ellaia   +3 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Supply Chain Management Overview: A Global Team Effort [PDF]

Supply chains have eliminated U.S.
Cliff Welborn
core  

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

System Oriented Sustainable Supply Chain Management Innovations in Automotive Industry - Skoda Auto Case Study [PDF]

, 2016
Jiří Ceé, Oleksii Dieiev, David Holman, Radim Lenort, David Staš, Pavel Wicher   +5 more
openalex   +1 more source