Results 241 to 250 of about 1,832,123 (358)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Digital supply chain transformation improves corporate carbon emission efficiency in Chinese listed companies. [PDF]

Sci Rep
Wei J, Zhang X, Cheng Y.
europepmc   +1 more source

Ellátási lánc kapcsolatok modellezése = Modeling of supply chain relationships [PDF]

, 2010
Andrea Gelei, Imre Dobos, Erzsébet Kovács   +2 more
openalex  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Blockchain-Enabled Traceability in the Rice Supply Chain: Insights from the TRACE-RICE Project. [PDF]

Foods
Gonçalves C, Fernandes J, Brites C.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Impact of extreme weather events on the US domestic supply chain of food manufacturing. [PDF]

Proc Natl Acad Sci U S A
Yim H, Dall'erba S.
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Tracing microbial hazards in the aquatic supply chain: challenges, technologies, and future directions. [PDF]

Front Nutr
Zhang J, Ding T, Ahn J, Zhang Z, Liao X.
europepmc   +1 more source

Bilateral matching process and decision analysis for QoS-based manufacturing supply chain partner selection [PDF]

Jing Gao, Sisi Liu, Tao Guan, Gao Yang, Tao Ma   +4 more
openalex   +1 more source