Results 61 to 70 of about 335,915 (265)

Framework for demand chain and supply chain coordination

open access: yesInternational Journal of Services Sciences, 2012
Organisations must coordinate the value creation (demand chain) and the value delivery (supply chain) processes in order to survive in today's competitive market environment.
Per Hilletofth, Lauri Lättilä
openaire   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Supply Chain Coordination Model with Retailerfs Risk Attitudes [PDF]

open access: yes
One of the major concerns in supply chain management is the coordination among various members of a supply chain comprising suppliers, manufacturers, distributors, wholesalers and retailers. We consider a newsvendor model in a two level supply chain with
Huy CHHAING
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The effects of the lack of coordination within the supply chain [PDF]

open access: yes
The present article refers to the bullwhip effect that negatively influences the supply chain performance. This effect is experienced by various industries, from fast moving consumer goods to IT products. The consequences for the supply chain members are
Carmen Balan
core  

Customer Enquiry Management in a Global Competitive Context: A Comparative Multi-Case Study Analysis [PDF]

open access: yes, 2008
Business-to-Business (B2B) relationships, such as between a manufacturer and a customer, are increasingly important during the Customer Enquiry Management (CEM) process, particularly so for non-Make-To-Stock (non-MTS) companies operating in industrial ...
Hendry, L, Stevenson, M, Zorzini, M
core  

Dynamic Coordination of Supply Chains

open access: yes, 2003
Business-to-business exchanges have become a common form of procurement due to their advantages regarding flexibility (such as the ability of being able to quickly change business partners), although the mean procurement prices are generally higher compared to long-term contracts. On the other side, a lot of procurement managers still believe that long-
openaire   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

IMPROVING VERTICAL COORDINATION OF AGRICULTURAL INDUSTRIES THROUGH SUPPLY CHAIN MANAGEMENT [PDF]

open access: yes
Supply chain management is an important topic related to improving efficiency, vertical coordination, overall performance and competitiveness in food industries.
Ricks, Donald J.   +2 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

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