Results 101 to 110 of about 58,819 (265)

Enhancing Supply Chain Resilience Through Supply Chain Finance: Moderating Role of Supply Chain Disruption

open access: yesPakistan Journal of Commerce and Social Sciences
Developing countries face economic disruptions due to financing limitations generated by traditional financing practices. Although supply chain finance (SCF) is recognized as a significant financing strategy in academic literature, it is still overlooked as a proactive financial strategy to mitigate disruptions.
Shahzad, Aamir, Irfan, Muhammad
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Exploring the mitigating role of sustainable innovation in supply chain disruption risks under the digital economy

open access: yesInternational Review of Economics & Finance
In light of the growing prominence of supply chain disruption risks, it has become increasingly important to examine how the digital economy can mitigate operational risks faced by enterprises.
Haoyu Bai, Yuntan Chen, Ziyu Zhang
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Geopolitical disruptions and supply chain structural ambidexterity

open access: yesInternational Journal of Operations & Production Management
PurposeThis paper seeks insights into how multinational enterprises restructure their global supply chains to manage the uncertainty caused by geopolitical disruptions. To answer this question, we investigate three significant geopolitical disruptions: Brexit, the US-China trade war and the coronavirus disease 2019 (Covid-19) pandemic.Design ...
Hamid Moradlou   +4 more
openaire   +2 more sources

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

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