Results 51 to 60 of about 727,322 (352)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Quantifying Credit Risk of Supply Chain Finance: A Chinese Automobile Supply Chain Perspective

open access: yesIEEE Access, 2019
Credit risk is a major risk of supply chain finance business, and it has recently gained increasing attention. Due to the high dependence between enterprises, the assessment of the supply chain finance risk will be more complicated. In the current study,
Min Zhang   +3 more
doaj   +1 more source

A Study on Risk of Supply Chain Finance——Take the Supply Chain Finance Business of Company A for Example [PDF]

open access: yes, 2015
供应链金融,这种新兴的融资方式,为商业银行拓展了新的业务和市场,也为各个产业,尤其是产业链条中的中小企业拓宽了新的融资途径。但,供应链金融所蕴含的风险也更为巨大,因为它不再以单个企业作为评价基础,而是综合考察核心企业的信用评价和物流监管企业运营情况对整条供应链上的企业进行授信。因此,在供应链金融迅速发展的背景下,正确分析其存在的风险问题具有一定的现实意义。 本文主要采用定性分析和案例研究相结合的方法,以核心企业的视角展开,从道德风险、操作风险等角度分析供应链金融的风险问题。首先,对供应链金融的概念 ...
王支良
core  

Ethical Implications of Predictive Risk Intelligence [PDF]

open access: yes, 2019
open access articleThis paper presents a case study on the ethical issues that relate to the use of Smart Information Systems (SIS) in predictive risk intelligence.
Jiya, Tilimbe
core   +1 more source

Overcoming SMEs Financing and Supply Chain Obstacles by Introducing Supply Chain Finance [PDF]

open access: yesInternational Journal of Business and Management, 2018
Keeping in view the importance of small and medium enterprises (SMEs) for the growth of a nation, we must also keep an eye on the challenges faced by those SMEs. There are various kinds of financing and supply chain options available for SMEs but they still face lot of hindrances.
Waseem Ahmed Abbasi   +2 more
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The Application and Optimization Path of Supply Chain Finance in Financing for Small and Medium-Sized Enterprises [PDF]

open access: yesSHS Web of Conferences
With the acceleration of economic globalization and market competitiveness, small and mediumsized businesses confront numerous problems in extending their business and capital operations.
Teng Youming
doaj   +1 more source

Supply chain finance: A systematic literature review and bibliometric analysis

open access: yesInternational Journal of Production Economics, 2018
Supply Chain Finance (SCF) is an effective method to lower financing costs and improve financing efficiency and effectiveness, and it has gained research momentum in recent years. This paper adopts a systematic literature review methodology combined with
Xin Xu   +5 more
semanticscholar   +1 more source

Blockchain Technology Adoption in Supply Chain Finance

open access: yesJournal of Theoretical and Applied Electronic Commerce Research, 2021
Supply Chain Finance (SCF) faces the complex problem of implementing inventory, purchase order and accounts receivable financing automation in terms of transaction data trust and validation.
Arief Rijanto
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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