Results 121 to 130 of about 614,587 (306)

Investigating the Feasibility of Open Development of Operations Support Solutions

open access: yes, 2005
The telecommunications Operations Support Systems supply chain must address many stakeholders: R&D, Product and Requirements Management, Purchasing, Systems Integration, Systems Administration and Users.
Gallen, Craig, Reeve, Jeffrey
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

The Effect of Supply Chain Integration, Management Commitment, and Sustainable Supply Chain Practices on Non-profit Organizations Performance Using SEM-FsQCA: Empirical Evidence in Afghanistan [PDF]

open access: yes
This study investigates the impact of supply chain integration, management commitment, and sustainable supply chain practices on non-profit organization performance. The research, centered on non-profit organizations in Afghanistan, employs Structural
Shahzad, Sayed Khalid
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

The effect of supply chain integration, management commitment, and sustainable supply chain practices on non-profit organizations performance using SEM-FsQCA: Evidence from Afghanistan

open access: yesSustainable Futures
This study explores the impact of supply chain integration, management commitment, and sustainable supply chain practices on the performance of non-profit organizations in Afghanistan.
Sayed Khalid Shahzad   +4 more
doaj   +1 more source

Validation of suply chain integration scales and the effect that size, level of vertical integration, industry and country have on their value [PDF]

open access: yes, 2012
Academic literature would appear to indicate that supply chain integration is a major factor in explaining the performance of companies. The results are nevertheless inconclusive.
Alfalla Luque, Rafaela   +2 more
core  

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