System Dynamics Simulation to Test Operational Policies in the Milk-Cheese Supply Chain Case study: Piar Municipality, Bolivar State, Venezuela. [PDF]
, 2008 With the purpose of detecting the impact that variations of demand cause in the milk-cheese supply chain, and determining how the operational policies of capacity, inventories or labor force can mitigate this impact, a system dynamics simulation model ...
Fuentes-Pila Estrada, Joaquin +2 more
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Investigating the relationship between digital technologies, supply chain integration and firm resilience in the context of COVID-19. [PDF]
Ann Oper Res, 2022 Cui L, Wu H, Wu L, Kumar A, Tan KH.
europepmc +1 more source
Investigating supply chain performance and supply chain integration linkage in Jordanian manufacturing firms. [PDF]
, 2018 Supply chain integration plays a major role in the success of any organisation. As a result in last over a decade it has drawn a significant interest from the research community and practitioners alike.
Garza-Reyes, Jose Arturo +4 more
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The mediating effect of information sharing on pharmaceutical supply chain integration and operational performance in Ethiopia: an analytical cross-sectional study. [PDF]
J Pharm Policy Pract, 2022 Birhanu Y +4 more
europepmc +1 more source
Enhancing the integration of agri-food supply chains: theoretical issues and practical challenges in the UK malting barley supply chain [PDF]
The purpose of this paper is to explore the issues that may affect the integration (i.e., the relationships) between the different actors that comprise a supply chain.
Leat, Philip M.K., Revoredo-Giha, Cesar
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Architectures for Green-Field Supply Chain Integration: Supply Chain Integration Design
, 2015 This paper applied case study research to design architectures for green-field supply chain integration. The integration design is based on a case study of a supply chain integration of 5 companies, operating in different, but supply chain complimenting industry sectors.
openaire +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source