Results 141 to 150 of about 611,924 (357)

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Achieving Supply Chain Resilience: The Role of Digital Transformation and Supply Chain Process Integration in Market Uncertainty

open access: yesJurnal Aplikasi Manajemen
In Indonesia's logistics sector, the challenges exacerbated by the COVID-19 pandemic highlight the urgent need for a supply chain. While digital transformation offers a promising solution, its impact remains to be determined.
Elizabeth Maeko Cyrilla Handijaya   +2 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Integration of dairy farms in supply chain in bulgaria [PDF]

open access: yes
This paper presents a new business model for an effective market inclusion of numerous small-scale dairy farms developed by a private entrepreneur. Firstly, it gives insight on development and challenges of Bulgarian dairy sector.
Bachev, Hrabrin
core   +1 more source

Pengaruh Organizational Culture Terhadap Entrepreneurial Intensity Dan Supply Chain Integration Dalam Rangka Memperoleh Competitive Advantage Pada Perusahaan Jasa Keuangan Di Surabaya [PDF]

open access: yes, 2014
Penelitian ini bertujuan untuk mengetahui pengaruh langsung yang signifikan dari organizational culture terhadap entrepreneurial intensity, entrepreneurial intensity terhadap competitive advantage, organizational culture terhadap supply chain integration,
Caroline, A. (Anita)
core  

Cloud computing, Web 2.0 and Operational Performance: The Mediating Role of supply chain integration

open access: yesIranian Journal of Information Processing & Management, 2018
This article is the impact of cloud computing (cloud computing) and Web 2.0 on the company's operating performance review. The intermediary role played by the integration of the supply chain will be analyzed.
Mahmoud Lari Dashtbayaz   +1 more
doaj  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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