Results 41 to 50 of about 561,297 (356)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

The influence of information technology integration on firm performance through supply chain quality and supply chain resilience [PDF]

open access: yesDecision Science Letters
Products produced by manufacturing companies are always required to meet the requirements set by customers. Manufacturing companies need to maintain product quality by involving internal company components and external partners by using integrated ...
Sautma Ronni Basana   +5 more
doaj   +1 more source

Multi agent system for negotiation in supply chain management [PDF]

open access: yes, 2008
Supply chain management (SCM) is an emerging field that has commanded attention and support from the industrial community. Supply chain (SC) is defined as the chain linking each entity of the manufacturing and supply process from raw materials through to
Makatsoris, C, Saberi, S
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Supply chain integration and resilience in Namibia’s state-owned logistics enterprises at Walvis Bay Port

open access: yesJournal of Transport and Supply Chain Management
Background: Drawing upon the supply chain integration model, this research examined the impact of supply chain integration on resilience. Building resilient supply chains has become paramount because of the complex nature of the contemporary environment.
Anatolia T. Shooya, Patmond T. Mbhele
doaj   +1 more source

Integration: A supply chain view [PDF]

open access: yesStrategic Management, 2014
Integration has different connotations to different disciplines. Here, we evaluate integration from a supply chain perspective. Organizations neither want, nor need to be integrated with their suppliers and supply chains for every product they buy. What,
Buddress Lee
doaj  

The Effect Of Supply Chain Risk on Resilience: Mediation Role of Supply Chain Integration

open access: yesJournal of International Trade, Logistics and Law, 2023
This study aims to examine the effect of supply chain risk on supply chain resilience through the mediation of supply chain integration. A sample was collected by purposive sampling, and the data was gathered by using an online survey for three company ...
Mariam Mahira   +2 more
doaj  

The effect of supply chain integration on information sharing:Enhancing the supply chain performance

open access: yesProcedia - Social and Behavioral Sciences, 2011
AbstractPrior research on supply chain management (SCM) suggests that information sharing has become a major driver of competitive advantage. In the context of increasingly globalized and competitive economy where organizations are part of an environment characterized by networks of inter- and intra-organizational relationships, an important ...
İnce, Hüseyin   +3 more
openaire   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy