Results 211 to 220 of about 46,250 (239)

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Antitumoral Efficacy of AuNRs‐Laden ECFCs In Vitro and In Vivo: Decoding the Heat and Rays Combo Treatment in Breast Cancer and Melanoma Cells

Advanced Healthcare Materials, EarlyView.
Endothelial Colony Forming Cells (ECFCs) acted as cellular cyborgs, stealthily transporting gold nanorods (AuNRs) into tumors to enable targeted near‐infrared (NIR) hyperthermia combined with radiotherapy. This approach triggers ferroptosis in melanoma and inhibits autophagy in breast cancer, revealing a tumor‐specific response to nanomaterial‐assisted
Cecilia Anceschi, Francesca Scavone, Paolo Armanetti, Luca Menichetti, Claudia Catarinicchia, Claudia Borri, Fulvio Ratto, Filippo Micheletti, Noemi Formica, Jessica Ruzzolini, Elena Frediani, Anastasia Chillà, Francesca Margheri, Mirko Severi, Rita Traversi, Patrizia Nardini, Daniele Guasti, Mario Del Rosso, Tommaso Del Rosso, Lisa Giovanelli, Cinzia Talamonti, Monica Mangoni, Isacco Desideri, Silvia Burchielli, Fabiola Pajar, Gabriella Fibbi, Anna Laurenzana   +26 more
wiley   +1 more source

Advancing from MOFs and COFs to Functional Macroscopic Porous Constructs

Advanced Materials, EarlyView.
This review study investigates the recent progress and methodologies for manufacturing metal–organic framework (MOF) or covalent–organic framework (COF)‐based 3D structured macroscopic porous constructs with high structural integrity, providing the possibility to control their porosity across dimensions.
Seyyed Alireza Hashemi, Ahmadreza Ghaffarkhah, Ali Akbar Isari, Mahyar Panahi‐Sarmad, Feng Jiang, Orlando J. Rojas, Stefan Wuttke, Mircea Dincă, Mohammad Arjmand   +8 more
wiley   +1 more source

Stochastic models for Supply Chain Management: The effects of decentralization

, 2003
Ziad Jemai
openalex   +1 more source

Challenges in Supply Chain Management and Supply Chain Management Accounting [PDF]

, 2020
The chapter provides an overview of the key challenges management accounting is confronted with in a supply chain environment. It outlines why and how cross-organizational collaboration differs from intracompany collaboration. Governance and coordination systems differ considerably between an individual firm and a network of multiple firms.
Andreas Taschner, Michel Charifzadeh
openaire   +1 more source

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Supply Chains, Supply Chain Management and Management Accounting

2020
The chapter defines the key concepts of management accounting, logistics, supply chains, and supply chain management (SCM) and discusses the interrelations between them. Management accounting is the internal accounting system that supports managers in carrying out management tasks.
Andreas Taschner, Michel Charifzadeh
openaire   +2 more sources

Supply chain management practices in toy supply chains

Supply Chain Management: An International Journal, 2005
PurposeInnovative products usually experience highly unpredictable and variable demand. This is especially valid for the volatile and seasonal toy industry, which produces high obsolete inventory, lost sales and markdown. In such a volatile industry, what supply chain management (SCM) practices are applicable and effective?
Arlbjørn, Jan Stentoft, Johansen, J., Wong, C. Y.   +2 more
openaire   +4 more sources

Supply Chain Management

2023
Supply chain management is an integral part of companies and organizations and is essential for the success of any company or organization and customer satisfaction. Considering the importance of this issue, in this chapter, first, the general and basic concepts of supply chain management, which include; The evolutionary course of supply chain ...
Hosseinzadeh Lotfi, F., Allahviranloo, T., Shafiee, M., Saleh, H.   +3 more
openaire   +2 more sources

Health Supply Chain Management

2010
This chapter gives an educational overview of:
Pat Gallagher, Rolf Zimmerman
openaire   +2 more sources

Supply Chain Management: An Overview

2000
What is the essence of Supply Chain Management (SCM)? How does it relate to Advanced Planning? In which sense are the underlying planning concepts “advanced”? What are the origins of SCM? These as well as related questions will be answered in this chapter.
openaire   +2 more sources