Results 41 to 50 of about 98,884 (268)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Performance Evaluation of a Supply Chain Network

Procedia Computer Science, 2013
AbstractThe supply chain network design and evaluation is a critical and difficult decision in a supply chain management. In this paper, we present a new method for evaluating the performance of a supply chain network. The main index is cost factors, which include four categories: production costs, disruption costs, co-ordination costs, and ...
Tinggui Chen, Xiaoqing Gong
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Evaluating industry 4.0 and sustainable industrial transformation through economic environmental and operational dynamics

Discover Sustainability
This systematic literature review analyzes the impact of Industry 4.0 (I4.0) on sustainable industrial transformation. Drawing from 100 peer-reviewed articles published between 2017 and 2024, sourced from the Scopus and Web of Science databases, we ...
Hadi Mareeh, Munirah Sarhan Alqahtani, Fozi Ali Belhaj, Ahmed Alwadeai   +3 more
doaj   +1 more source

Networked Analysis Approach of Supply Chain Network

Journal of Networks, 2014
With the development of global economy, the problems that supply chain management are facing become more and more complex. It is very necessary for the supply chain managers to apply new theories and methods to maintain the security of supply chain network.
openaire   +1 more source

Designing a Sustainable Supply Chain Network

, 2019
This paper deals with the design of a sustainable supply chain in a high variety production environment. To respond to this challenge, a Mixed-Integer Linear Programming model is proposed. The economic criteria are the costs of transportation, and that of opening and operating manufacturing facilities; the environmental criterion is the level of CO2 ...
Moreno-Camacho, Carlos, Montoya-Torres, Jairo, Jaegler, A.   +2 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Hierarchical graph-based integration network for propaganda detection in textual news articles on social media

Scientific Reports
During the Covid-19 pandemic, the widespread use of social media platforms has facilitated the dissemination of information, fake news, and propaganda, serving as a vital source of self-reported symptoms related to Covid-19.
Pir Noman Ahmad, Jiequn Guo, Nagwa M. AboElenein, Qazi Mazhar ul Haq, Sadique Ahmad, Abeer D. Algarni, Abdelhamied A. Ateya   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source