Results 61 to 70 of about 98,884 (268)

On the optimization of supply chain networking decisions

open access: yesEuropean Journal of Operational Research, 2001
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Salem Y. Lakhal   +3 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Cooperation in the supply chain network

open access: yesForum Scientiae Oeconomia, 2017
Experts often mention the fact that nowadays neither products nor enterprises, but supply chains rather are competing in the market. The companies and participants will be the winners who can satisfy customers’ dynamically changing needs faster and more
Tímea Kozma
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Using the Analytical Network Process to Select the Best Strategy for Reducing Risks in a Supply Chain

open access: yesJournal of Engineering, 2013
This paper considers four types of the most prominent risks in the supply chain. Their subcriteria and relations between them and within the network are also considered. In a supply chain, risks are mostly created by fluctuations.
L. Hosseini   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Role of Optimal Production Plan at the Focal Firm in Optimization of the Supply Chain

open access: yesJournal of Management and Research, 2014
Supply chain management and optimization is a critical aspect of modern enterprises and an expanding area of research. Modeling and optimization are the traditional tools of supply chain management.
M.M. HARIS ASLAM   +2 more
doaj   +1 more source

Disruption cascades in supply chain networks [PDF]

open access: yes, 2018
Supply chain disruptions result in substantial losses that can arise not only due to direct shocks at firms (eg., due to natural disasters or factory fires), but also from the interruption of normal operations at the suppliers' or buyers' ends; that is, due to disruptions cascading from supply chain partners in the adjacent tiers and beyond. The extent
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Home - About - Disclaimer - Privacy