Results 131 to 140 of about 955,442 (303)
Relationships among Healthcare Digitalization, Social Capital, and Supply Chain Performance in the Healthcare Manufacturing Industry. [PDF]
Int J Environ Res Public Health, 2021 Kim HK, Lee CW.
europepmc +1 more source
GResilient index to assess the greenness and resilience of the automotive supply chain [PDF]
Purpose: The purpose of this paper is to suggest an Index entitled GResilient Index to assess the greenness and resilience of the automotive companies and corresponding supply chain. Design/methodology/approach: An integrated assessment model is proposed
Azevedo, Susana G. +3 more
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The Influence of Supply Chain Digitalization on Integration and Agility in Company Performance
Indonesian Interdisciplinary Journal of Sharia EconomicsThis study aims to analyze the effect of supply chain digitalization on integration and agility in company performance. Supply chain digitalization is considered a key factor in improving operational efficiency and effectiveness.
Ikrima Ikrima +2 more
doaj +1 more source
Transparency in the Pork Supply Chain: Comparing China and The Netherlands [PDF]
We present a research plan to assess the value of transparency by comparing pork supply chains in The Netherlands and China.We assume that chain performance depends on chain configuration, which depends on societal context and its associated quality ...
Hofstede, Gert Jan, Osinga, Sjoukje A.
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
The effects of the lack of coordination within the supply chain [PDF]
The present article refers to the bullwhip effect that negatively influences the supply chain performance. This effect is experienced by various industries, from fast moving consumer goods to IT products. The consequences for the supply chain members are
Carmen Balan
core
Improving supply chain performance
The thesis's main objective is to develop mathematical models and algorithms for optimising two important supply chain management problems, namely the warehouse order picker routing problem and the multi-commodity network design problem. The second chapter of this thesis presents a graph reduction algorithm for solving the Travelling Salesman Problem ...
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source