Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Inter-firm Relationships and Performance Factors in the Australian Beef Supply Chain: Implications for the Stakeholders [PDF]
Recent study by Meat & Livestock Australia revealed that cost competitiveness and market development issues in supply chain are the major factors for a long term decline of the Australian Beef industry. This study, based on the explanation of transaction
Islam, Nazrul +2 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Digital transformation, smart technologies, and eco-innovation are paving the way toward sustainable supply chain performance. [PDF]
Sci Prog, 2022 Rehman Khan SA +3 more
europepmc +1 more source
The effect of supply chain collaboration on supply chaıin performance
Pressacademia, 2017 Purpose- The purpose of this study is to to analyze the relationship between Supply Chain Collaboration (SCC) and Supply Chain Performance (SCP). Methodology- A conceptual model with theoretical basis is developed as a causal model that can be operationalized using Statistical Package for the Social Science (SPSS).
DOGANAY, Ahmet, ERGUN, Sinem
openaire +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Social sustainable supply chain performance assessment using hybrid fuzzy-AHP-DEMATEL-VIKOR: a case study in manufacturing enterprises. [PDF]
Environ Dev Sustain, 2022 Guo R, Wu Z.
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Impact of Recycler Information Sharing on Supply Chain Performance of Construction and Demolition Waste Resource Utilization. [PDF]
Int J Environ Res Public Health, 2022 Zheng H +9 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source