Results 71 to 80 of about 117,452 (262)

Leveraging Digital Innovation for Sustainable Performance via Supply Chain Resilience

open access: yesJournal of Theoretical and Applied Electronic Commerce Research
As an emerging innovation paradigm in the digital economy era, digital innovation has become an important means for manufacturing firms to build supply chain resilience for sustainable development, but its intrinsic mechanism requires clarification. This
Yuhan Liu   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The effect of supply chain integration, management commitment, and sustainable supply chain practices on non-profit organizations performance using SEM-FsQCA: Evidence from Afghanistan

open access: yesSustainable Futures
This study explores the impact of supply chain integration, management commitment, and sustainable supply chain practices on the performance of non-profit organizations in Afghanistan.
Sayed Khalid Shahzad   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The impact of artificial intelligence on sustainable development performance of public healthcare supply chain-an empirical study based on listed Chinese pharmaceutical companies

open access: yesFrontiers in Public Health
With the continuous deepening of the digital transformation of the public healthcare supply chain, as the next step of digitalization, intelligent transformation has received much attention, especially how artificial intelligence can improve the ...
Qianlan Chen   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Linking supply chain risk management to financial performance of SMEs: can supply chain collaboration moderate?

open access: yesAfrican Business Management Journal
While supply chain risk management is widely recognised for mitigating disruptions and enhancing operational efficiency, its impact on the financial performance of manufacturing small and medium-sized enterprises remains underexplored, particularly when
Michael Patrick Chuwa   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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