Results 81 to 90 of about 156,131 (313)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Performance Evaluation of a Supply Chain Network

open access: yesProcedia Computer Science, 2013
AbstractThe supply chain network design and evaluation is a critical and difficult decision in a supply chain management. In this paper, we present a new method for evaluating the performance of a supply chain network. The main index is cost factors, which include four categories: production costs, disruption costs, co-ordination costs, and ...
Tinggui Chen, Xiaoqing Gong
openaire   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The Role of Digitalization, Agility, and Capability on Integration and Its Impact on Performance: A Study on the Retail Healthcare Supply Chain in Jakarta

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to examine the impact of digitalization in the supply chain on different elements of supply chain management. Based on the presented research and analysis, it can be concluded that supply chain digitalization positively impacts supply ...
Devina Devina   +2 more
doaj   +1 more source

Lean, green practices and process innovation: a model for green supply chain performance [PDF]

open access: yes, 2018
This paper investigates the relationship between lean, process innovation, green practices and green supply chain management performance. Data were gathered by surveying 374 firms in the manufacturing supply chain industry.
Vikas Kumar   +12 more
core   +1 more source

Supply chain performance and preferential procurement in Gauteng government departments

open access: yes, 2022
Background: In the previous two decades, preferential procurement and supply chain performance have gained popularity within academics following the introduction of the Preferential Procurement Policy Framework Act No 05 of 2000 (PPPFA) which was aimed ...
Tshikovhi, Ndivhuho, Sibanda, Beatah
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Enhancing the supply chain performance of Kayumas specialty coffee based on the SCOR-ANP approach

open access: yesAGROMIX
Introduction: Performance evaluation is essential in defining supply chain strategies because the firm can find out how the business processes in the supply chain are running and formulate strategic policies.
Aisya Risanda   +2 more
doaj   +1 more source

Collaborative supply chain modelling and performance measurement

open access: yes, 2002
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 11/12/2002.For many years, supply chain research focused on operational aspects and therefore mainly on the optimisation of parts of the production and ...
Angerhofer, Bernhard J.   +1 more
core  

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