Results 61 to 70 of about 33,271 (299)

The resilience and determinants of global mineral resource supply chains: a network percolation perspective

open access: yesFrontiers in Earth Science
Mineral resources are the basic materials for global economic development. Assessing mineral resource supply chain resilience is an important pillar of mineral resource supply chain stability management.
Huiling Zheng   +5 more
doaj   +1 more source

Triple bottom line aspects and sustainable supply chain resilience: A structural equation modelling approach

open access: yesFrontiers in Environmental Science, 2023
The purpose of this paper is to investigate which of sustainability elements, in the context of triple bottom line (TBL), are used to build sustainable supply chain resilience.
Blanka Tundys, Tomasz Wiśniewski
doaj   +1 more source

A complex system, agent based model for studying and improving the resilience of production and distribution networks [PDF]

open access: yes, 2007
The very complexity and the extended reach of today’s globe-spanning supply chain networks, the low inventory levels and lack of redundancies required to achieve efficient operations expose businesses to a huge range of unexpected disruptions.
Datta, Partha Priya
core  

Supply Chain Resilience Triangle: The Study and Development of a Framework

open access: yes, 2017
Supply Chain Resilience has been broadly studied during the last decade, focusing the research on many aspects of Supply Chain performance. Consequently, different definitions of Supply Chain Resilience have been developed by the research community ...
MARCUCCI, GIULIO   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Conceptual model for breaking ripple effect and cycles within supply chain resilience [PDF]

open access: yes, 2022
Business world has reached a complexity tipping point, increasing the risk of disruption consequences not to remain localised in a single company but to reverberate on the entire Supply Chain.
Mazzuto G.   +9 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Research on the Influencing Factors and Promotion Strategies of Food Supply Chain Resilience

open access: yesLiang you shipin ke-ji
The resilience of food supply chain is related to food security. It is of practical significance to explore the influencing factors of the resilience of food supply chain.
HAN Guang-he   +3 more
doaj   +1 more source

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