Results 101 to 110 of about 1,279,777 (376)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Chemical Emergency Supply Chain Risk Evaluation and Mitigation for Major Natural Disasters
Chemical Engineering Transactions, 2017 The operation of the chemical emergency supply chain may be destroyed by the risk events, such as major natural disasters and other emergencies, which can bring about the decreasing of node operating capacity.
Dali Jiang +4 more
doaj +1 more source
Supply chain risk perception: understanding the gap between theory and practice. [PDF]
, 2018 The risks inherent in the supply chain threaten the effectiveness and the output of the chain. It is capable of hampering the growth and performance of organizations whose goods pass through a supply chain.
Adebola Adeseun, Maria +3 more
core +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Supply Chain Coordination Model with Retailerfs Risk Attitudes [PDF]
One of the major concerns in supply chain management is the coordination among various members of a supply chain comprising suppliers, manufacturers, distributors, wholesalers and retailers. We consider a newsvendor model in a two level supply chain with
Huy CHHAING
core
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
Chemical Fuel Supply Chain Integration and Optimization under the Influence of Uncertain Factors
Chemical Engineering Transactions, 2018 The petrochemical industry belongs to the dangerous chemical industry. The optimization of supply chain can significantly improve the overall profits of enterprises, reducing costs and risks.
Liu Liu
doaj +1 more source
Modeling and analysis of supply chain risk system under the influence of partners' collaboration [PDF]
, 2011 Confining the focus to individual enterprise, traditional risk management literature seems to echo inadequately in the context of collaborative supply chain, partially due to its exclusion of correlation of risks across companies.
Yen, BPC, Zeng, B
core +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source