Results 31 to 40 of about 146,215 (303)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Business Review, 2023 This study investigates the impact of supply chain resilience and robustness on firm performance and also examines the significance of supply chain risk management (SCRM) in minimizing the consequences of disruptions on supply chain performance in the
Aalyan Munir +2 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Enhancing firm performance with supply chain risk management and supply chain resilience
Brazilian Journal of Operations & Production ManagementGoal: This study aims to investigate how supply chain risk management (SCRM) impacts firm performance (FP) in Karawo MSMEs, while also considering the mediating role of supply chain resilience (SCR) and the moderating influence of supply chain ...
Moh Ramdhan Arif Kaluku +3 more
doaj +1 more source
Risk of the Maritime Supply Chain System Based on Interpretative Structural Model
Polish Maritime Research, 2017 Marine transportation is the most important transport mode of in the international trade, but the maritime supply chain is facing with many risks.
Jiang He, Xiong Wei, Cao Yonghui
doaj +1 more source
Quantifying Credit Risk of Supply Chain Finance: A Chinese Automobile Supply Chain Perspective
IEEE Access, 2019 Credit risk is a major risk of supply chain finance business, and it has recently gained increasing attention. Due to the high dependence between enterprises, the assessment of the supply chain finance risk will be more complicated. In the current study,
Min Zhang +3 more
doaj +1 more source
A multi-period risk sharing supply chain contract under consideration of price and demand uncertainties [PDF]
, 2021 Isil Tari
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source