Results 51 to 60 of about 147,439 (262)

A risk assessment model for supply chains

Pressacademia, 2018
Purpose- This research proposes an integrated methodology to assess the risks in supply chains. Methodology- Regarding the importance of risk management in supply chains, an integrated model including Failure Mode Effects Analysis (FMEA), Analytic Hierarchy Process (AHP) and Weighted Product (WP) is proposed.
CANBAKİS, Sena Kubra, KARABAS, Melike, KİLİC, Huseyin Selcuk, KOSEOGLU, Sedef, UNAL, Ezgi   +4 more
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Supply chain risks in the South African manufacturing sector

Journal of Transport and Supply Chain Management
Background: Supply chain operations in many organisations are becoming vulnerable to increasing supply chain risks because of unforeseen events that can disrupt the flow of goods and services across the value chain.
Rudzani Tshifhumulo, Gert J. Heyns, Peter J. Kilbourn   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Gold supply risk in the ASGM engaged countries: bibliometric-based approach

Environmental Research: Infrastructure and Sustainability
To achieve stable supply and procurement of gold, it is crucial to focus on mining activities located upstream in the supply chain and to evaluate the associated supply chain risk.
Shion Yamao, Shoki Kosai, Shunsuke Kashiwakura, Eiji Yamasue, Kenichi Nakajima   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Linking supply chain risk management to financial performance of SMEs: can supply chain collaboration moderate?

African Business Management Journal
While supply chain risk management is widely recognised for mitigating disruptions and enhancing operational efficiency, its impact on the financial performance of manufacturing small and medium-sized enterprises remains underexplored, particularly when
Michael Patrick Chuwa, Furaha Edwin Mlay, Ambali Kitalima   +2 more
doaj   +1 more source

Two revenue sharing contracts in a three-echelon supply chain with a risk-neutral or a risk-averse retailer

Journal of Industrial Engineering and Management, 2015
Purpose: This paper compares the efficiency of two revenue-sharing contracts and discusses the members’ preference for a three-echelon supply chain with the retailer’s different risk attitude.
Yumei Hou, Fangfang Wei, Xin Tian, Xiaoyun Liu   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Meminimasi Risiko pada Rantai Pasok Menggunakan Kerangka Kerja Suplly Chain Risk Management di PT. Adhi Chandra Dwiutama

Rekayasa Hijau: Jurnal Teknologi Ramah Lingkungan, 2019
ABSTRAK Rantai Pasok merupakan jaringan dari perusahaan- perusahaan yang bekerja secara bersama untuk menciptakan dan mengantarkan suatu produk ke konsumen akhir.
Arief Irfan Syah Tjaja, Dio Rizcki Sekartyasto, Arif Imran   +2 more
doaj   +1 more source