Results 61 to 70 of about 146,215 (303)

Meminimasi Risiko pada Rantai Pasok Menggunakan Kerangka Kerja Suplly Chain Risk Management di PT. Adhi Chandra Dwiutama

open access: yesRekayasa Hijau: Jurnal Teknologi Ramah Lingkungan, 2019
ABSTRAK Rantai Pasok merupakan jaringan dari perusahaan- perusahaan yang bekerja secara bersama untuk menciptakan dan mengantarkan suatu produk ke konsumen akhir.
Arief Irfan Syah Tjaja   +2 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The role of supply chain risk mitigation strategies to manage supply chain disruptions

open access: yesJournal of Transport and Supply Chain Management
Background: Supply chain disruptions have always existed, but have become more intense during the last decade or so. Factors in the macro environment have also contributed and none more so than during the coronavirus disease 2019 (COVID-19) pandemic.
Jacobus D. Nel
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Supply chain risk management

open access: yesSupply Chain Management: An International Journal, 2004
This article presents a secondary analysis of the literature, supplemented by case studies to determine if large companies increase their exposure to risk by having small‐ and medium‐size enterprises (SMEs) as partners in business critical positions in the supply chain, and to make recommendations concerning best practice.
openaire   +3 more sources

The impact of supply chain risk and supply chain integration on organizational performance

open access: yesBrazilian Journal of Operations & Production Management
Goal: The purpose of this study is to investigate the mediating role of supply chain integration for Supply chain risks heading toward organizational performance. This study is mainly focused on the dairy sector of emerging economies.
Tahir Malik   +2 more
doaj   +1 more source

Evolutionary Game Dynamics for Financial Risk Decision-Making in Global Supply Chain

open access: yesComplexity, 2018
This paper focuses on the game evolution process and its influencing factors of financial risk cooperation behavior between suppliers and manufacturers in global supply chain system.
Zhi Li, Guanghao Jin, Shen Duan
doaj   +1 more source

Chemical Fuel Supply Chain Integration and Optimization under the Influence of Uncertain Factors

open access: yesChemical Engineering Transactions, 2018
The petrochemical industry belongs to the dangerous chemical industry. The optimization of supply chain can significantly improve the overall profits of enterprises, reducing costs and risks.
Liu Liu
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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