Results 41 to 50 of about 67,171 (286)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Meminimasi Risiko pada Rantai Pasok Menggunakan Kerangka Kerja Suplly Chain Risk Management di PT. Adhi Chandra Dwiutama

open access: yesRekayasa Hijau: Jurnal Teknologi Ramah Lingkungan, 2019
ABSTRAK Rantai Pasok merupakan jaringan dari perusahaan- perusahaan yang bekerja secara bersama untuk menciptakan dan mengantarkan suatu produk ke konsumen akhir.
Arief Irfan Syah Tjaja   +2 more
doaj   +1 more source

Evaluation of supply chain risks by fuzzy DEMATEL method: a case study of iron and steel industry in Turkey

open access: yesInternational Journal of Production Management and Engineering, 2022
Business practices to strengthen competitiveness increase the vulnerability of supply chains to risks. Risks that can adversely affect the effectiveness and efficiency of supply chain activities are events that disrupt the flow of information, materials,
Asuman Üstündağ   +3 more
doaj   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

Supply Chain Disruption Models: A Critical Review

open access: yesLogistics Research, 2018
Enterprises affected by supply chain disruptions have reported adverse consequences and dramatic financial losses. Within the research area of supply chain risk management, researchers use simulation models and algorithms to analyze disruption risks ...
Niels Bugert, Rainer Lasch
doaj   +1 more source

Research on key nodes identification of aviation manufacturing supply chain based on complex network

open access: yesHangkong gongcheng jinzhan, 2023
With the increasing instability and the participation of more participants in the aviation manufacturing supply chain,the risks faced by the management of the aviation manufacturing supply chain is also increased.
HUANG Hui, LI Ruiqi
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Stochastic Supply Chain Optimization with Risk Management

open access: yesChemical Engineering Transactions, 2019
This paper presents the hypothetical case study of supply-chain management of the carbon dioxide-utilization products where its feedstock is sewage gas containing mostly methane and CO2. This supply chain begins with three suppliers sending sewage gas of
Narut Suchartsunthorn, Kitipat Siemanond
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

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