Results 131 to 140 of about 168,543 (317)

Understanding the System Context of Alternative Food Supply Chains

This paper focuses upon the case of alternative food supply chains (AFSCs) as a "laboratory" for the implementation of sustainability concepts on a larger scale.
Vuylsteke, Anne, Van Huylenbroeck, Guido
core  

Agricultural and food business dynamics in the Mediterranean region: Identifying key indicators for sustainable supply chain systems originated by small-scale farming production

New Medit
Fruit and vegetables play a crucial role in ensuring food and nutrition security, and developing more sustainable value chains in agriculture and the agri-food sector.
Paolo Prosperi, Yazdan Soltanpour, Sina Ahmadi Kaliji, Lhoucine Ouahi, Mohamed Ait Hou, Charisios Achillas, Hager Ahmed, Dimitrios Aidonis, Luca BARTOLI, Marcello DE ROSA, Ahmed Ghannouchi, Justus Harm, Evagelos D. Lioutas, Teresa Terilli, Luca CAMANZI   +14 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

GINI’s Odyssey in Greece: Econometric Analysis of Income Inequality, GDP, and Unemployment Through Economic Phases (Pre-Crisis, Crisis, Memoranda, and Post-Memoranda)

International Journal of Financial Studies
This study explores the relationship between income inequality, economic growth, and unemployment in Greece from 2003 to 2020, encompassing key economic phases: pre-crisis, crisis, memoranda, and post-memoranda. The aim is to analyze how economic growth (
Panagiotis Karountzos, Nikolaos T. Giannakopoulos, Damianos P. Sakas, Kyriaki I. Efthalitsidou, Stavros P. Migkos   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Exploring hybridity in food supply chains

In recent years, a number of dynamic aspects of food supply chains have attracted great interest among social scientists investigating rural restructuring and change. These include: the expansion of organic agriculture; the development of new value added
Kirwan, James, Slee, William
core  

Securing Renewable Energy Supply Chains: Challenges and Opportunities for Information Security

Renewable energy supply chains play a crucial role in the transition to a sustainable and low carbon energy system. However, as the renewable energy sector evolves and embraces advanced technologies, such as Industry 4.0 and the emerging Industry 5.0 ...
Dabo, Al-Amin Abba, Amin, Hosseinian, Adisa, Olalekan   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Innovation and Governance in International Food Supply Chains: The Cases of Ghanaian Pineapples and South African Grapes

This paper reports an exploratory case study on innovation in, and governance of, international supply chains originating in developing countries. Two African fruit export chains are analyzed: the table grape chain from South Africa (a highly developed ...
Trienekens, Jacques H., Willems, Sabine
core