Results 51 to 60 of about 106,849 (261)

Digital Marketing and Consumer Behavioral Psychology: The Transformation of Brand Marketing Mode [PDF]

SHS Web of Conferences
The advent of the digital age has brought new challenges to the traditional marketing model, and the changes in consumer behavior and psychology have also prompted profound changes in the brand marketing model.
Li Ang
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Conveying intermittent water supply schedules digitally: production burdens and consumption possibilities in Coimbatore, India

Environmental Research: Infrastructure and Sustainability
Intermittently available piped water imposes unequal mental, physical, and financial stresses on a billion water users worldwide. These burdens lighten when water is supplied according to a reliable and accessible supply schedule.
Nidhi Subramanyam, David D J Meyer
doaj   +1 more source

Russian Logistics and Supply Chain Management: Challenges and Relevant Solutions

Управленческие науки
Relevance of the research. The article considers a forced paradigm shift and systemic restructuring of Russian logistics due to the introduction of sanctions barriers and partial trade blockade, which, in addition to restricting Russian exports and ...
К. V. Simonov
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Digital Marketing Strategies and Performance of Tour Operators Supply Chain in the Tourism Industry

International Journal of Business, Economics, and Social Development
Digital marketing strategies are vital in enhancing the performance of tour operators’ supply chains within the tourism sector, increasing visitor numbers, sales, and profit, indirectly affecting the economic growth of a community.
Boniface Emmanuel Mwalukasa
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Supporting ecosystem for farmers' food traceability participation: A systematic review

Journal of Agriculture and Food Research
Food traceability from ‘farm to fork’ enhances supply chain transparency and ensures food safety, quality, and authenticity. Farmers play a pivotal role in enabling traceability by digitally recording production processes and input data and sharing this ...
Airong Zhang, Christina Maxwell, Francesco Tacconi, Alyce Lythall, David Smith, Xinlong Guan   +5 more
doaj   +1 more source