Results 231 to 240 of about 10,115,754 (295)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Maternal Misperception of Child Body Size and Its Association with Information-Seeking Opportunities and Information Sources in Japanese Preschool Children. [PDF]

Children (Basel)
Kobayashi T, Sasaki K, Tada Y, Wada Y, Yokoyama T.   +4 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Manganese (Mn) doping effects on the structure and surface characteristics of copper zinc tin sulphide (CZTS) transition metal sulphides synthesised <i>via</i> a sol-gel method. [PDF]

RSC Adv
Najitha AR, Che Balian SR, Ahmoum H, Omar FS, Chelvanathan P, Su'ait MS.   +5 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Hydrodistillation, comparative analysis and optimization of essential oils from Thymus schimperi R, Thymus serrulatus R, and Ocimum lamiifolium Hochst ex Benth. [PDF]

Sci Rep
Mebrate SB, Alemu AF, Tegegne AM, Tadesse MG, Bezabuh GK.   +4 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Evolutionary modularity of the primate vestibular system: Morphological distinction of otolithic and canalicular organs. [PDF]

PNAS Nexus
Smith CM, Laitman JT.
europepmc   +1 more source

Influence of nitrogen functional groups in carbon-based supports anchoring Pt nanoclusters and single atoms for efficient ammonia borane hydrolysis.

Chem Commun (Camb)
Barlocco I, Bellomi S, Anghinelli BMC, Chen X, Delgado JJ, Stucchi M, Prati L, Föttinger K, Villa A.   +8 more
europepmc   +1 more source