Results 131 to 140 of about 3,741,726 (317)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Bayesian networks for mastitis management on dairy farms

, 2009
This manuscript presents the idea of providing dairy farmers with probability distributions to support decisions on mastitis management and illustrates its feasibility by two applications. Naive Bayesian networks were developed for both applications. The
Barkema, H.W., Decision Support Systems, van der Gaag, M.A., Gaag, M.A., van der, Steeneveld, Wilma, van der Gaag, Linda, Steeneveld, W., Sub Decision Support Systems begr 1/1/13, Hogeveen, H.   +8 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Decision Support Systems [PDF]

Yearbook of Medical Informatics, 1993
openaire   +3 more sources

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Resource Efficient Scheduling, Optimization and Control.

, 2014
This report documents the program and the outcomes of Dagstuhl Seminar 14181 "Multi-agent systems and their role in future energy grids". A number of recent events (e.g.
Valogianni, Konstantina, Zhang, Minjie, van den Akker, Marjan, Sub Decision Support Systems, Mönch, Lars, Decision Support Systems, Derksen, Christian, Ketter, Wolfgang, Huhns, Michael, Saffre, Fabrice, Unland, Rainer, van Heck, Erik, Kowalczyk, Ryszard   +12 more
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Higher education decision making and decision support systems

The authors illustrate several issues in decision support and decision support systems (DSS), state of the art research in these fields, and also their own studies in designing a higher education DSS.
Ghisoiu, Nicolae, Bresfelean, Vasile Paul   +1 more
core  

Residential Energy Dataset with Electric Vehicles, Photovoltaic Generation and Tariff Variability in Ireland

Scientific Data
Household energy demand data are essential for designing load-shifting strategies, storage solutions and demand response programs. This is the first publicly available dataset that integrates multiple household-level energy and mobility metrics.
Dimitris Avgoloupis, Vasilis Michalakopoulos, Elissaios Sarmas, Vangelis Marinakis, Mario Couto, Alessio Coccia, Mariana Jimenez   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source