Results 221 to 230 of about 34,927,484 (291)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Meta-analysis of extremotolerant microbes to address nutrient deficiencies in bioregenerative life support systems during Deep-space Missions. [PDF]

NPJ Sci Food
Ellena G, Mazzoli A, Spacova I, Leys N, Lebeer S, Mastroleo F.   +5 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Decision factors for the selection of AI-based decision support systems-The case of task delegation in prognostics. [PDF]

PLoS One
Heinrich K, Janiesch C, Krancher O, Stahmann P, Wanner J, Zschech P.   +5 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Aquatic bryophytes as biofilters and resource regenerators in Bioregenerative Life Support Systems: the moss on Mars project. [PDF]

Front Plant Sci
Amitrano C, Arena C, De Pascale S, Pugliese M, Barozzi F, Fanizzi FP, De Micco V, di Sansebastiano GP.   +7 more
europepmc   +1 more source

Parental perspectives on school attendance problems and the role of municipal support systems. [PDF]

Front Child Adolesc Psychiatry
Hansen UI, Munkhaugen EK, Larsen K.
europepmc   +1 more source

Immune challenges and pathogen risks in edible insects: safeguarding health in space life-support systems. [PDF]

Front Physiol
Jensen AB, Copplestone D, Guidetti R, Heer M, Pittia P, Berggren Å.   +5 more
europepmc   +1 more source