Results 81 to 90 of about 3,741,726 (317)

A two-phase method for extracting explanatory arguments from Bayesian networks [PDF]

, 2017
Errors in reasoning about probabilistic evidence can have severe consequences. In the legal domain a number of recent miscarriages of justice emphasises how severe these consequences can be.
Sub Intelligent Systems, Timmer, Sjoerd T., Meyer, J.J.C., Renooij, S., Meyer, John Jules Ch, Intelligent Systems, Sub Decision Support Systems, Prakken, Henry, Prakken, H., Verheij, B., Renooij, Silja, Timmer, S.T., Decision Support Systems, Sub Simulation of Complex Systems, Verheij, Bart, Verheij, Bart; id_orcid   +15 more
core   +1 more source

Reshaping the energy landscape of Crete through renewable energy valleys

Scientific Reports
Renewable energy valleys (REVs) represent a transformative concept poised to reshape global energy landscapes. These comprehensive ecosystems transition regions from conventional energy sources to sustainable, self-reliant hubs for renewable energy ...
Panagiotis Skaloumpakas, Elissaios Sarmas, Michalis Rachmanidis, Vangelis Marinakis   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Learning from incomplete data in Bayesian networks with qualitative influences [PDF]

, 2016
Domain experts can often quite reliably specify the sign of influences between variables in a Bayesian network. If we exploit this prior knowledge in estimating the probabilities of the network, it is more likely to be accepted by its users and may in ...
Sub Algorithmic Data Analysis, Algorithmic Data Analysis, Decision Support Systems, Sub Decision Support Systems, van der Gaag, L.C., Feelders, A.J., Masegosa, Andrés   +6 more
core   +1 more source

Methodologies and Handling Techniques of Large-Scale Information in Decision Support Systems for Complex Missions

Applied Sciences
Designing integrating systems for support, real-time monitoring, and executing of complex missions is challenging, since they often fail due to high levels of complexity and overwhelming volume of input data.
George Tsavdaridis, Constantin Papaodysseus, Nikolaos V. Karadimas, George Papazafeiropoulos, Athanasios Delis   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Collaborative Systems in Support of Reindustrialization [PDF]

, 2013
The establishment of collaborative business ecosystems is widely accepted as a key strategy in the reindustrialization processes. This is clearly present in the ongoing policy discussions and industry-oriented research roadmaps. A brief analysis of recent contributions to the PRO-VE conference shows the active role already played by the collaborative ...
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source