Results 101 to 110 of about 3,741,726 (317)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Decision support systems [PDF]
Decision Support Systems (DSS) are a specific class of computerized information system that supports business and organizational decision-making activities.
Georgiana MARIN
core
, 2018 As business environment is getting more and more turbulent, effective strategic management and decision-making is necessary, thus the implementation of decision support systems (DSS) is considered crucial to sustain competitive advantage.
Kitsios, Fotis, Kamariotou, Maria
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Online social support: an exploratory study of breastfeeding women’s use of internet and mobile applications to obtain peer support [PDF]
, 2012 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Online social support is reported to be used by a number of people to obtain social interaction and exchange communication as a way to buffer stressful ...
Burman, Ana Beatriz Santana
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Emergent Frameworks for Decision Support Systems [PDF]
Knowledge is generated and accessed from heterogeneous spaces. The recent advances in in-formation technologies provide enhanced tools for improving the efficiency of knowledge-based decision support systems.
Florin Gheorghe FILIP +1 more
core +1 more source
From arguments to constraints on a Bayesian network
, 2016 In this paper, we propose a way to derive constraints for a Bayesian Network from structured arguments. Argumentation and Bayesian networks can both be considered decision support techniques, but are typically used by experts with different backgrounds ...
Scheffler, Tatjana +9 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Evolution of Decision Support Systems Research Field in Numbers [PDF]
The scientific production in a certain field shows, in great extent, the research interests in that field. Decision Support Systems are a particular class of information systems which are gaining more popularity in various domains.
Marius CIOCA +3 more
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