Results 51 to 60 of about 7,794,647 (291)
Bird Species Recognition Using Support Vector Machines
Automatic identification of bird species by their vocalization is studied in this paper. Bird sounds are represented with two different parametric representations: (i) the mel-cepstrum parameters and (ii) a set of low-level signal parameters, both of ...
Seppo Fagerlund
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Modelling Proteolytic Enzymes With Support Vector Machines
The strong activity felt in proteomics during the last decade created huge amounts of data, for which the knowledge is limited. Retrieving information from these proteins is the next step. For that, computational techniques are indispensable.
Morgado Lionel +3 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Analysis of support vector machines [PDF]
We compare L1 and L2 soft margin support vector machines from the standpoint of positive definiteness, the number of support vectors, and uniqueness and degeneracy of solutions. Since the Hessian matrix of L2 SVM is positive definite, the number of support vectors for L2 SVM is larger than or equal to the number of L1 SVM.
openaire +3 more sources
Mean-Variance optimal portfolio selection integrated with support vector and fuzzy support vector machines [PDF]
This study introduces a novel approach integrating a support vector machine (SVM) with an optimal portfolio construction model. Leveraging the Radial Basis Function (RBF) kernel, the SVM identifies assets with higher growth potential.
Simrandeep Kaur +2 more
doaj +1 more source
Minimal Complexity Support Vector Machines for Pattern Classification
Minimal complexity machines (MCMs) minimize the VC (Vapnik-Chervonenkis) dimension to obtain high generalization abilities. However, because the regularization term is not included in the objective function, the solution is not unique.
Shigeo Abe
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Data Mining via Support Vector Machines [PDF]
Support vector machines (SVMs) have played a key role in broad classes of problems arising in various elds. Much more recently, SVMs have become the tool of choice for problems arising in data classi - cation and mining.
Mangasarian, Olvi
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

