Results 191 to 200 of about 4,809,971 (303)

Cancer patients' insights and experience of palliative and supportive care in the UAE: a qualitative study. [PDF]

Front Oncol
AlOlama KM, Alameri SO, Wissi Y, Alabdli WM, AlHammadi HH, AlDhaheri AG, AlNaqbi MA, Elshafey MA, Abushousha N, Al-Shamsi AHO, Al-Shamsi SHO, Al-Shamsi MHO, Kalantar AT, Y Alfoteih A, Basioni AM, Alkrad W, Abdelwahab SI, Balushi AA, Iqbal F, Nijhawan NA, Al-Shamsi HO.   +20 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Content and design considerations for digital supportive care tools for patients with cancer: A textual statistical analysis of patients', relatives', and healthcare professionals' perspectives. [PDF]

PLoS One
Zanni L, Rebillon M, Naeyaert A, Fournier V, Laroussi-Libeault L, Justin P, Antoine P, Haryan C, Richez L, Lamore K.   +9 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Dentists' knowledge and practices in supportive care: a French national survey. [PDF]

Support Care Cancer
de Bataille C, Prunier C, Saucourt M, Epstein JB, Vigarios E, Maret D.   +5 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Psychodermatologic Dimensions of Psoriasis: Perceived Burden, Help-Seeking Behavior and Openness to Supportive Care. [PDF]

J Clin Med
Tarcau BM, Vata D, Popescu IA, Olinici DT, Postu A, Halip IA, Gheuca Solovastru DF, Mocanu M, Gaina MA, Gheuca Solovastru L.   +9 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Family caregivers of children with cystic fibrosis: supportive care needs - scoping review. [PDF]

BMJ Support Palliat Care
Shadi D, Jabraeili M, Hassankhani H, Alhani F, Arshadi Bostanabad M.   +4 more
europepmc   +1 more source