3D printing of acetaminophen suppository and its quality and pharmacokinetic evaluation [PDF]
Introduction Acetaminophen is a widely used antipyretic and analgesic treatment. Becuase oral administration poses a risk of acute liver failure, researchers are exploring alternative routes of administration using 3D printing. Methods This study reports
Ming Chen +8 more
doaj +2 more sources
Biochemical evaluation of Jihua hemostatic suppository in hemorrhagic internal hemorrhoids: Modulation of XPO1, VEGF, and collagen I/III expression and inflammatory biomarkers [PDF]
Background: Hemorrhagic internal hemorrhoids involve abnormal vascular remodeling, inflammatory activation, and extracellular matrix dysregulation.
Wang Chao +6 more
doaj +2 more sources
Rectal delivered nanocomposite suppository against radiation-induced proctitis [PDF]
Background Radiation-induced proctitis is a common complication of radiotherapy for pelvic malignancies, for which effective local treatments remain limited.
Jixu Lu +3 more
doaj +2 more sources
Formulation, Physiochemical, and Microbial Assay of Henna Oil Vaginal Suppository Formulated with Polyethylene Glycol Bases [PDF]
Background: Persian Medicine is one of the oldest and richest complementary and alternative options in the field of medicine and has a comprehensive medical system.
Payam Khazaeli +5 more
doaj +1 more source
Management of Postcaesarean Delivery Analgesia-Diclofenac Suppository, Paracetamol Infusion and a Combination [PDF]
Introduction: One of the most important aspect of postoperative care is pain management which plays an important role in early recovery and improves patient’s general condition. Paracetamol and diclofenac have an excellent safety profile when compared
Mandem Sadana Reddy +1 more
doaj +1 more source
Preparations of Rectal Suppositories Containing Artesunate
Rectal artesunate suppositories are a useful option for pre-referral treatment of severe malaria, specifically in children under 6 years of age in remote malaria-endemic areas.
Suzanne Persaud +4 more
doaj +1 more source
The effect of Apotel and Diclofenac suppository on pain relief after cesarean section among primiparous women: A randomized double-blind clinical trial study [PDF]
Introduction: Inadequate pain control after caesarean can have adverse effects on various body systems, cause the mother not pay attention to the baby and problems in the breastfeeding process.
Maryam Aradmehr +4 more
doaj +1 more source
Thermogravimetric study of vinpocetine suppository
Introduction. Development of technology is the one of the main stage in creation of new medications. Technological process of suppository manufacturing includes sufficiently long thermoprocessing during suppository base making, addition of the active ...
N. А. Nаgоrnaya +2 more
doaj +1 more source
Possibilities of microemulsion application in rectal administration of indomethacin
Rectal administration is a suitable route of administration for drugs that are either very irritating to the intestine (e.g., indomethacin) or are more effective when the first-pass effect in the liver is circumvented.
Špaglová M. +5 more
doaj +1 more source
THERMOGRAVIMETRIC INVESTIGATIONS OF VAGINAL SUPPOSITORY WITH THYME OIL
One of the main stages in new medicines creation is the development of their making technology. Technological process of suppository making includes ratherlongthermal treatment during preparation and homogenization of suppository base, active ...
N. V. Melnikova +2 more
doaj +1 more source

