Results 161 to 170 of about 9,264 (223)

Clinical trial: a novel high-dose 1 g mesalamine suppository (Salofalk) once daily is as efficacious as a 500-mg suppository thrice daily in active ulcerative proctitis.

open access: yesInflammatory Bowel Diseases, 2010
BACKGROUND: Mesalamine suppositories are first-line therapy in active ulcerative proctitis; the standard regime still recommends multiple doses per day. The primary objective of this study was to show the noninferiority of once-daily administration of a ...
Ingolf Cascorbi   +2 more
exaly   +2 more sources

Designing and Developing Suppository Formulations for anti-HIV Drug Delivery

open access: yesTherapeutic Delivery, 2017
Despite a long history of use for rectal and vaginal drug delivery, the current worldwide market for suppositories is limited primarily due to a lack of user acceptability.
Anthony S Ham, Robert W Buckheit
exaly   +2 more sources
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Radiopaque Suppositories

Radiology, 1976
The authors describe the radiographic appearance of several commonly used rectal suppositories. Such drugs are sufficiently opaque to be seen on abdominal radiographs and may simulate excreted urographic contrast medium or stones. Errors in interpretation can be avoided by asking the patient about rectal medication or by taking lateral or delayed films.
A, Spitzer, S B, Caruthers, D P, Stables
openaire   +2 more sources

Anorectal suppositories

Diseases of the Colon & Rectum, 1966
A review of the therapeutic uses of anorectal suppositories is given. The major local effects of suppositories are production of defecation, topical therapy, and relief of pain. Systemic actions are possible from drugs that can be absorbed through the rectal mucosa.
openaire   +2 more sources

Stability of misoprostol in suppositories

American Journal of Health-System Pharmacy, 2005
Misoprostol is a prostaglandin E1 analogue originally marketed for use in the treatment of peptic ulcer disease. The practice of rectally administering misoprostol in doses of up to 1000 μg for obstetric use seems to be proliferating around the world.[1][1]–[4][2] Rectal administration ...
Halim, Hafirassou   +4 more
openaire   +2 more sources

Preparation of progesterone suppositories

American Journal of Health-System Pharmacy, 1977
The manufacture and assay of progesterone suppositories by a hospital pharmacy department are described. The compounding formula and procedures are presented. The product is used to treat luteal phase insufficiency.
B D, Roffe, R A, Zimmer, H J, Derewicz
openaire   +2 more sources

Hydrophilic Suppository Bases

Journal of the American Pharmaceutical Association (Scientific ed.), 1950
The utility and versatility as suppository base materials of polyoxyalkylene derivatives of sorbitan partial fatty acid esters are described. These nontoxic, nonirritant, nonionic surface-active materials are particularly adaptable to suppository base formulation.
openaire   +2 more sources

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