Results 171 to 180 of about 2,659,694 (301)

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Viral Suppression Among People Living with HIV in Tajikistan: A Nationwide Analysis. [PDF]

Viruses
Alaei K, Kwan B, Lounsbery CP, Abdullozoda J, Yusufi SJ, Cortez P, Tiwana M, Nguyen J, Torabzadeh HR, Alaei A.   +9 more
europepmc   +1 more source

Suppressive Soils

Annual Review of Phytopathology, 1983
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Variability and methodological choices in articulatory suppression tasks: a review. [PDF]

Front Psychol
De Livio C, Gervasi AM, Falcinelli I, Fini C, Maggio F, Brozzoli C, Borghi AM.   +6 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Prevalence and correlates of low-level viremia and viral load non-suppression among adults on HIV treatment: Results from the Tanzania HIV Impact Survey, 2022-2023. [PDF]

PLoS One
Sumba S, Kailembo A, Ismail A, Njau P, Wang A, Mchau G, Revocatus B, Taluka EA, Mayige M, Nkumbula T, Faki FH, Malewo O, Moremi N, Karugendo E, Issa F, Masemo A, Laws R, Patel D, Maruyama H, Kamwela J, El-Sadr W, Mgomella GS, Swaminathan M, Porter S, Khatib A.   +24 more
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Achieving Effective Batch-to-Batch Error Correction through Suppression Correction and Dual MSTUS Normalization. [PDF]

Anal Chem
Ghosh D, Kar J, de Jong FA, Beecher C, Shulaev V.   +4 more
europepmc   +1 more source

Acid suppression.

BMJ, 1990
openaire   +3 more sources