Results 61 to 70 of about 243,790 (263)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The benefits of coronavirus suppression: A cost-benefit analysis of the response to the first wave of COVID-19 in the United States.

open access: yesPLoS ONE, 2021
This paper estimates the benefits and costs of state suppression policies to "bend the curve" during the initial outbreak of COVID-19 in the United States.
James Broughel, Michael Kotrous
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A Convenient and Robust Test to Quantify Interocular Suppression for Children With Amblyopia

open access: yesi-Perception, 2019
Interocular suppression was quantified by the interocular luminance difference that was needed when the two eyes were balanced in discriminating a black–white stripe formed butterfly stimulus, which was dichoptically presented through polarized glasses ...
Hui Chen   +10 more
doaj   +1 more source

Application of a Mathematical Model in Determining the Spread of the Rabies Virus: Simulation Study

open access: yesJMIR Medical Informatics, 2020
BackgroundRabies is an acute infectious disease of the central nervous system caused by the rabies virus. The mortality rate of rabies is almost 100%.
Huang, Yihao, Li, Mingtao
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Measurements of Jet Suppression with ATLAS

open access: yesNuclear Physics A, 2013
AbstractMeasurements of inclusive jet suppression in Pb + Pb collions at sNN=2.76 TeV with the ATLAS detector are reported. The centrality, pT and jet size dependence of the central-to-peripheral ratio, RCP, is presented. The results indicate that jets are suppressed by approximately a factor of two in the most central collisions, and a significant ...
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Suppressing measurement noise in logical qubits through measurement scheduling

open access: yesPhysical Review A
Quantum error correction is essential for reliable quantum computation, where surface codes demonstrate high fault-tolerant thresholds and hardware efficiency. However, noise in single-shot measurements limits logical readout fidelity, forming a critical bottleneck for fault-tolerant quantum computation.
Xu, Xiao-Yue, Ding, Chen, Bao, Wan-Su
openaire   +2 more sources

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