Results 71 to 80 of about 243,790 (263)

Emotion regulation strategies and mental wellbeing among Chinese college students during COVID-19: the moderating roles of confinement and attentional bias

open access: yesFrontiers in Psychology
BackgroundDuring COVID-19, confinement measures were implemented to curb the epidemic spread. While effective in reducing infections, these measures likely deteriorated the psychological wellbeing of students due to school closures and isolation ...
Mengqi Xiao   +10 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Hair Zidovudine Concentrations Predict Virologic Outcomes Among People Living with HIV/AIDS in China

open access: yesPatient Preference and Adherence, 2022
Yan Wu,1– 3,* Shuaifeng Liu,4,* Liuxi Chu,1– 3 Quan Zhang,5,6 Jin Yang,3,7 Shan Qiao,5 Xiaoming Li,5 Yuejiao Zhou,4 Huihua Deng,1– 3 Zhiyong Shen4 1Department of Brain and Learning Science, School of Biological Science & Medical Engineering ...
Wu Y   +9 more
doaj  

Temporal analysis of image-rivalry suppression.

open access: yesPLoS ONE, 2012
During binocular rivalry, perception alternates between two different images presented one to each eye. At any moment, one image is visible, dominant, while the other is invisible, suppressed.
Rishi Bhardwaj, Robert P O'Shea
doaj   +1 more source

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