Results 301 to 310 of about 880,593 (358)
An education in tolerance: the 2025 Nobel Prize in Physiology or Medicine.
Dis Model MechListon A.
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Expression of concern: "Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression" [Heliyon 10 (2024) e23875]. [PDF]
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Neuron, 1991
For the past decade, cellular oncogenes have attracted the attention of biologists intent on understanding the molecular origins of cancer. As the present decade unfolds, oncogenes are yielding their place at center stage to a second group of actors, the tumor suppressor genes, which promise to teach us equally important lessons about the molecular ...
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For the past decade, cellular oncogenes have attracted the attention of biologists intent on understanding the molecular origins of cancer. As the present decade unfolds, oncogenes are yielding their place at center stage to a second group of actors, the tumor suppressor genes, which promise to teach us equally important lessons about the molecular ...
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Current Opinion in Genetics & Development, 1994
The mutation of tumor suppressor genes is thought to contribute to tumor growth by inactivating proteins that normally act to limit cell proliferation. Several tumor suppressor proteins have been identified in recent years, but only two of them, p53 and pRb, are understood in detail.
P W, Hinds, R A, Weinberg
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The mutation of tumor suppressor genes is thought to contribute to tumor growth by inactivating proteins that normally act to limit cell proliferation. Several tumor suppressor proteins have been identified in recent years, but only two of them, p53 and pRb, are understood in detail.
P W, Hinds, R A, Weinberg
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Suppressor T Cells and Suppressor Factor
Hospital Practice, 1978The ability to suppress antibody response to specific antigens has been found to be inherent in a subpopulation of T lymphocytes. The suppressor pathway has been shown to involve an initial T-cell clone that that elaborates a soluble factor which, in turn, induces a second cohort of effector cells.
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1974
Suppressors are genes which suppress the expression of mutant phenotypes. The suppressors can be considered to be mutant genes themselves since they are generally not found in the wild type strains but are obtained by selecting for revertants of the mutant phenotype.
D C, Hawthorne, U, Leupold
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Suppressors are genes which suppress the expression of mutant phenotypes. The suppressors can be considered to be mutant genes themselves since they are generally not found in the wild type strains but are obtained by selecting for revertants of the mutant phenotype.
D C, Hawthorne, U, Leupold
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The Journal of Immunology, 1972
Abstract The antigen-induced DNA synthetic response of a number of different thymocyte populations was studied in the spleens of lethally irradiated recipients by incorporation of 125I 5-iodo-2-deoxyuridine. The response of certain cell combinations was not only less than the sum of the two responding alone but less than one of the ...
Gershon, R K +3 more
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Abstract The antigen-induced DNA synthetic response of a number of different thymocyte populations was studied in the spleens of lethally irradiated recipients by incorporation of 125I 5-iodo-2-deoxyuridine. The response of certain cell combinations was not only less than the sum of the two responding alone but less than one of the ...
Gershon, R K +3 more
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Journal of Cell Science, 1988
ABSTRACT Genes that can inhibit the expression of the tumorigenic phenotype have been detected by the fusion of normal and malignant cells, the phenotypic reversion of in vitro transformants, the induction of terminal differentiation of malignant cell lineages, the loss of ‘recessive cancer genes’, the discovery of regulatory sequences ...
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ABSTRACT Genes that can inhibit the expression of the tumorigenic phenotype have been detected by the fusion of normal and malignant cells, the phenotypic reversion of in vitro transformants, the induction of terminal differentiation of malignant cell lineages, the loss of ‘recessive cancer genes’, the discovery of regulatory sequences ...
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