Results 71 to 80 of about 817,665 (309)

The Tobacco mosaic virus 126-kDa Protein Associated with Virus Replication and Movement Suppresses RNA Silencing

Molecular Plant-Microbe Interactions, 2004
Systemic symptoms induced on Nicotiana tabacum cv. Xanthi by Tobacco mosaic virus (TMV) are modulated by one or both amino-coterminal viral 126- and 183-kDa proteins: proteins involved in virus replication and cell-to-cell movement.
Xin Shun Ding, Jianzhong Liu, Ning-Hui Cheng, Alexey Folimonov, Yu-Ming Hou, Yiming Bao, Chika Katagi, Shelly A. Carter, Richard S. Nelson   +8 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23 [PDF]

, 2008
Background: Recurrent loss of part of the long arm of chromosome 11 is a well established hallmark of a subtype of aggressive neuroblastomas. Despite intensive mapping efforts to localize the culprit 11q tumour suppressor gene, this search has been ...
Evi Michels, Jasmien Hoebeeck, Katleen De Preter, Alexander Schramm, Bénédicte Brichard, Anne De Paepe, Angelika Eggert, Geneviève Laureys, Jo Vandesompele, Frank Speleman, WA Weiss, YP Mosse, D Trochet, V van Limpt, EF Attiyeh, J Vandesompele, C Guo, D Plantaz, J Vandesompele, J Vandesompele, CP Koiffmann, Y Mosse, SA Bader, K De Preter, JM Maris, E Michels, GM Brodeur, B Menten, B Berwanger, K De Preter, L McArdle, A Oberthuer, M Ohira, A Schramm, Q Wang, F Pattyn, F Pattyn, J Vandesompele, T Aranyi, GE Tusnady, F Pattyn, CJ Breen, ME Luttikhuis, S Griffiths-Jones, S Griffiths-Jones, R Spitz, L Gangwani, B Doran, GC Owens, AK Perl, J Roesler, P Fogar, H Sasaki, RA Blaheta, T Biederer, M Kuramochi, H Fukuhara, T Ito, Y Murakami, RD Steenbergen, EF Attiyeh, H Gomyo, M Alaminos, B Banelli, M Yageta, A Krause   +65 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

AGO2: a new Argonaute compromising plant virus accumulation

Frontiers in Plant Science, 2012
Plant viruses use several strategies to transport their nucleic acid genomes throughout the plants. Regardless of the movement mechanism, a universal major block to uninterrupted viral trafficking is the induction of antiviral silencing that degrades ...
Veria Y Alvarado, Herman B Scholthof
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Characterization of a Novel Polerovirus Infecting Maize in China

Viruses, 2016
A novel virus, tentatively named Maize Yellow Mosaic Virus (MaYMV), was identified from the field-grown maize plants showing yellow mosaic symptoms on the leaves collected from the Yunnan Province of China by the deep sequencing of small RNAs.
Sha Chen, Guangzhuang Jiang, Jianxiang Wu, Yong Liu, Yajuan Qian, Xueping Zhou   +5 more
doaj   +1 more source

Metastasis suppressor genes.

Histology and histopathology, 2013
Metastasis is a major cause of cancer mortality. Metastasis is a complex process that requires the regulation of both metastasis-promoting and metastasis suppressor genes. The discovery of metastasis suppressor genes contributes significantly to our understanding of metastasis mechanisms and provides prognostic markers and therapeutic targets in ...
Yan, Jinchun, Yang, Qin, Huang, Qihong
openaire   +3 more sources

DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration. [PDF]

, 2010
Deleted in liver cancer 1 (DLC1) is a RhoGTPase activation protein-containing tumor suppressor that associates with various types of cancer. Although DLC2 shares a similar domain structure with that of DLC1, the function of DLC2 is not well characterized.
Chen, N-T, Liao, Y-C, Lin, Y, Lo, SH, Shih, Y-P, Xue, L   +5 more
core   +3 more sources