Results 131 to 140 of about 52,059 (299)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Asymmetric triplex metallohelices with high and selective activity against cancer cells [PDF]

, 2014
Small cationic amphiphilic α-helical peptides are emerging as agents for the treatment of cancer and infection, but they are costly and display unfavourable pharmacokinetics.
David J. Fox, Peter Scott, Clarkson, Guy, Clarkson, Guy J., Scott, Peter, Fox, David J., Simpson, Daniel H., Guy Clarkson, Alan D. Faulkner, Roger M. Phillips, Phillips, Roger M., Qasem M. A. Abdallah, David I. Roper, Howson, Suzanne E., Faulkner, Alan D., Suzanne E. Howson, Rebecca A. Kaner, Pratik Gurnani, Roper, David I., Kaner, Rebecca A., Abdallah, Qasem M. A., Gurnani, Pratik, Daniel H. Simpson   +22 more
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

α‐Helix‐Driven Regulation of Aqueous Circularly Polarized Luminescence in Homopolypeptide Self‐Assembly

Aggregate
Biopolymer‐driven supramolecular chirality in aqueous media has gained significant advancements in hierarchical chiral nanostructures. However, researches on the aqueous circularly polarized luminescence (CPL) induced by supramolecular self‐assembly and ...
Jinhui Jiang, Ziyue Ye, Siwei Zhang, Fulong Ma, Lin Lu, Zijie Qiu, Jianwei Sun, Yu Xiong, Zheng Zhao, Jacky W. Y. Lam, Ben Zhong Tang   +10 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Supramolecular self-assembly in solid-state lithium batteries: Bulk electrolyte design and interface engineering

Supramolecular Materials
The development of solid-state lithium batteries (SSLBs) is pivotal to addressing the escalating global demand for advanced electrochemical energy storage systems, driven notably by electric vehicles and portable electronics.
Changjian Li, Shanbin Goh, Yu Ou, Chaoyue Sun, Shuaishuai Yan, Wenhui Hou, Yang Lu, Xiao Ma, Zhi Liu, Yuhao Wu, Yingchun Xia, Weili Zhang, Qingbin Cao, Hao Liu, Xuan Song, Xuwen Peng, Jian Feng, Kezhuo Li, Lai Wei, Jia Zhang, Jiahong Chen, Pan Zhou, Hangyu Zhou, Kai Liu   +23 more
doaj   +1 more source

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source

Amplification of chirality in surface-confined supramolecular bilayers

Nature Communications, 2018
One of the most dramatic effects of supramolecular assembly is the generation of homochirality in near-racemic systems. Here the authors rationalize the chiral amplification mechanism with a combined scanning tunneling microscopy and modelling study of ...
Hai Cao, Steven De Feyter
doaj   +1 more source

Dipole‐Manipulated Built‐In Electric Field Enables Ultrafast Charge Separation in Perylene Diimide Polymers for Photoelectrochemical Water Splitting

Advanced Science, EarlyView.
Molecular dipole engineering in dendritic perylene diimide polymers through nitrogen‐rich heterocyclic linkers amplifies the built‐in electric field, enabling sub‐picosecond charge separation and efficient multi‐electron accumulation. This structure–dynamics–performance relationship establishes a versatile design strategy for high‐performance organic ...
Ying‐Xin Qiao, Zicong Situ, Yi‐Jing Chen, Shuo‐Xiang Liu, Jing‐Lan Zhang, Xingqing Li, Luo‐Han Xie, Si‐Hang Xie, Qing‐Xiao Tong, Andong Xia, Zhuoran Kuang, Jing‐Xin Jian   +11 more
wiley   +1 more source

Supramolecular Self-Assembly.

Journal of Synthetic Organic Chemistry, Japan, 1995
This article reviews the recent development of the weak-bond-induced organization of well-defined structures, or supramolecular self-assembly. This phenomenon has been showing remarkable potential to construct architectural structures, such as helices, macrocycles, cages, tubes, grids, interlocked systems, etc., from programmed components through weak ...
openaire   +2 more sources