Results 1 to 10 of about 894 (176)
Supramolecular synthon hierarchy in sulfonamide cocrystals with syn-amides and N-oxides [PDF]
IUCrJ, 2019 Sulfonamide drugs are well known antibacterial and antimicrobial molecules for pharmaceutical development. Building a library of suitable supramolecular synthons for the sulfonamide functional group and understanding their crystal structures with partner
Geetha Bolla, Ashwini Nangia
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Assessment of Computational Tools for Predicting Supramolecular Synthons [PDF]
Chemistry, 2021 The ability to predict the most likely supramolecular synthons in a crystalline solid is a valuable starting point for subsequently predicting the full crystal structure of a molecule with multiple competing molecular recognition sites.
Bhupinder Sandhu +4 more
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Modular protein frameworks via supramolecular synthons. [PDF]
Biophys RevAbstract Controlled protein assembly and protein crystal engineering are routes to new types of biomaterials. In this review, we examine how crystal engineering concepts, including polymorph searching, molecular tectonics and supramolecular synthons, can be adapted and applied in protein-based systems.
Mockler NM, Crowley PB.
europepmc +3 more sources
Making and Breaking Supramolecular Synthons for Modular Protein Frameworks. [PDF]
ChemistryAbstractAnionic calixarenes are useful mediators of protein assembly. In some cases, protein – calixarene cocrystallization yields multiple polymorphs. Ralstonia solanacearum lectin (RSL) cocrystallizes with p‐sulfonato‐calix[8]arene (sclx8) in at least four distinct pH‐dependent arrangements.
Mockler NM, Raston CL, Crowley PB.
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Supramolecular Synthon Identification in Azelaic Acid – Isonicotinamide
Journal of Magnetic Resonance Open, 2022 Supramolecular synthons are the smallest structural units that contain the information inherent in building large molecular assemblies. Here, we apply solid-state NMR methods for the identification of the synthon in a cocrystal of Azelaic acid [(CH2)7 ...
Jayasubba Reddy Yarava +4 more
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Supramolecular Frameworks Based on Rhenium Clusters Using the Synthons Approach [PDF]
Molecules, 2021 The reaction of the K4[{Re6Si8}(OH)a6]·8H2O rhenium cluster salt with pyrazine (Pz) in aqueous solutions of alkaline or alkaline earth salts at 4 °C or at room temperature leads to apical ligand exchange and to the formation of five new compounds: [trans-
Nathalie Audebrand +5 more
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From a Binary to a Quaternary Cocrystal: An Unusual Supramolecular Synthon [PDF]
Angewandte Chemie - International Edition, 2019 AbstractFormation of a stoichiometric quaternary cocrystal consisting of resorcinol (RES), tetramethylpyrazine (TMP), phenazine (PHE) and pyrene (PYR) is described. A closed tetrameric resorcinol‐heterocycle synthon, unusual in that it has two different linker bases rather than just one, is observed in this four‐component solid.
Mithun Paul, Gautam Desiraju
exaly +4 more sources
The interplay between hydrogen bonds and stacking/T-type interactions in molecular cocrystals [PDF]
Communications ChemistrySupramolecular synthon and hydrogen bond pairing approaches have influenced the understanding of cocrystal formation for decades, but are hydrogen bonds really the dominant interaction in cocrystals?
Aurora J. Cruz-Cabeza +2 more
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The origin of synthons and supramolecular motifs: beyond atoms and functional groups. [PDF]
IUCrJA four-membered R 2 2 (4) supramolecular motif formed by S...S and S...I chalcogen-bonding interactions in the crystal structure of 4-iodo-1,3-dithiol-2-one (C 3 HIOS 2 ...
Shukla R +5 more
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Crystals, 2023 Single crystals of two polymorphic forms of 4′-methyl-2,4-dinitrodiphenylamine were obtained by crystallization and characterized by X-ray diffraction analysis.
Ivan V. Fedyanin, Aida I. Samigullina
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