Results 21 to 30 of about 894 (176)

Consistency and variability of cocrystals containing positional isomers: the self-assembly evolution mechanism of supramolecular synthons of cresol–piperazine

IUCrJ, 2019
The disposition of functional groups can induce variations in the nature and type of interactions and hence affect the molecular recognition and self-assembly mechanism in cocrystals. To better understand the formation of cocrystals on a molecular level,
Na Wang, Xin Huang, Lihang Chen, Jinyue Yang, Xin Li, Jiayuan Ma, Ying Bao, Fei Li, Qiuxiang Yin, Hongxun Hao   +9 more
doaj   +1 more source

Combinatorial selection of molecular conformations and supramolecular synthons in quercetin cocrystal landscapes: a route to ternary solids

IUCrJ, 2015
The crystallization of 28 binary and ternary cocrystals of quercetin with dibasic coformers is analyzed in terms of a combinatorial selection from a solution of preferred molecular conformations and supramolecular synthons.
Ritesh Dubey, Gautam R. Desiraju
doaj   +1 more source

Quaternary cocrystals: combinatorial synthetic strategies based on long-range synthon Aufbau modules (LSAM)

IUCrJ, 2016
A synthetic strategy is outlined whereby a binary cocrystal may be developed in turn into a ternary and finally into a quaternary cocrystal. The strategy hinges on the concept of the long-range synthon Aufbau module (LSAM) which is a large supramolecular
Ritesh Dubey, Niyaz A. Mir, Gautam R. Desiraju   +2 more
doaj   +1 more source

Multicomponent Crystal of Metformin and Barbital: Design, Crystal Structure Analysis and Characterization

Molecules, 2021
The formation of most multicomponent crystals relies on the interaction of hydrogen bonds between the components, so rational crystal design based on the expected hydrogen-bonded supramolecular synthons was employed to establish supramolecular compounds ...
Linhong Cai, Lan Jiang, Cong Li, Xiaoshu Guan, Li Zhang, Xiangnan Hu   +5 more
doaj   +1 more source

Rapidly Diversifying Hydrogen‐Bonded Organic Frameworks With Permanent Porosity

Angewandte Chemie, EarlyView.
This article reviews diversifying hydrogen‐bonded organic frameworks (HOFs) with permanent porosity reported over the past 15 years, based on the molecular structures of their constituent tectons. Furthermore, several distinctive aspects and concepts are described, such as permanent porosity, isostructural (isoreticular) HOFs, and multicomponent mixed ...
Taito Hashimoto, Ichiro Hisaki
wiley   +2 more sources

The First Insight Into the Supramolecular System of D,L-α-Difluoromethylornithine: A New Antiviral Perspective

Frontiers in Chemistry, 2021
Targeting the polyamine biosynthetic pathway by inhibiting ornithine decarboxylase (ODC) is a powerful approach in the fight against diverse viruses, including SARS-CoV-2.
Joanna Bojarska, Roger New, Paweł Borowiecki, Milan Remko, Martin Breza, Izabela D. Madura, Andrzej Fruziński, Anna Pietrzak, Wojciech M. Wolf   +8 more
doaj   +1 more source

Aniline–phenol recognition: from solution through supramolecular synthons to cocrystals

IUCrJ, 2014
Aniline–phenol recognition is studied in the crystal engineering context in several 1:1 cocrystals that contain a closed cyclic hydrogen-bonded [...O—H...N—H...]2 tetramer supramolecular synthon (II). Twelve cocrystals of 3,4,5- and 2,3,4-trichlorophenol
Arijit Mukherjee, Karuna Dixit, Siddhartha P. Sarma, Gautam R. Desiraju   +3 more
doaj   +1 more source

Designing Supramolecular Gelators: Challenges, Frustrations, and Hopes

Gels, 2019
This article is a personal account of the author, who serendipitously entered the field of supramolecular gels nearly two decades ago. A supramolecular synthon approach in the context of crystal engineering was utilized to develop a working hypothesis to
Parthasarathi Dastidar
doaj   +1 more source

Hydrogen-Bonding Motifs in Piperazinediium Salts

Crystals, 2014
Four novel organic salts of piperazine and 2-methylpiperazine with p-toluenesulfonic acid and chloroacetic acid have been synthesized and structurally characterized.
Chris S. Hawes, Cherry Chen, Andrew Tran, David R. Turner   +3 more
doaj   +1 more source

Crystal structure of 2,4-diamino-6-oxo-3,6-dihydropyrimidin-1-ium p-toluenesulfonate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title salt, C4H7N4O+·C7H7O3S−, the 2,6-diamino-4-oxo-1,3-dihydropyrimidin-1-ium cation interacts with the sulfonate group of the p-toluenesulfonate anion via a pair of N—H...O hydrogen bonds, forming a hetero-synthon R22(8) that mimics the role of
Krishnasamy Mamallan, Sadasivam Sharmila Tagore, Sundaramoorthy Gomathi, Velusamy Sethuraman   +3 more
doaj   +1 more source