Results 51 to 60 of about 4,377 (177)
Co-crystals of diflunisal and isomeric pyridinecarboxamides – a thermodynamics and crystal engineering contribution [PDF]
Diflunisal is an anti-inflammatory, non-steroidal drug, class II of the Biopharmaceutical Classification System, which has recently been the subject of renewed interest due to its potential for use in the oral therapy of familial amyloid polyneuropathy ...
Canotilho, João +6 more
core +1 more source
A donor–π–acceptor–π–donor (D–π–A–π–D) fluorophore bearing a U‐shaped dipyridophenazine core forms bifurcated hydrogen bonds with neutral donors such as sulfonamides or water. This interaction modulates both ground and excited states, enabling red‐shifted emission and enhanced photoluminescence in solution and solid state.
Kimiya Takei +7 more
wiley +1 more source
Formulation pre-screening of inhalation powders using computational atom-atom systematic search method [PDF]
This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.The synthonic modeling approach provides ...
Collins, Elizabeth +10 more
core +4 more sources
Prediction of supramolecular synthons and crystal packings of supramolecular HMX/solvent assemblies
We report the most stable packings of five HMX/solvent supramolecular assemblies.
Zhichao Liu +3 more
openaire +2 more sources
Triggered formation of thixotropic hydrogels by balancing competitive supramolecular synthons [PDF]
Two component hydrogels have been obtained by formation of 1:1 complexes of bis(pyridyl urea)s with a range of dicarboxylic acids. The gels are thixotropic and undergo an assembly process in which short segments can reversibly assemble into an interconnected fibrous network.
Liu, K., Steed, J. W.
openaire +3 more sources
This study exploits the comparable binding tolerances between the fluorinase enzyme and the A2A adenosine receptor towards the development of novel C‐2 functionalised 5′‐fluorodeoxy‐adenosine (FDA)‐based agonists with enzymatic 18F‐labelling capability for positron emission tomography (PET).
Nicolas Charalambous +6 more
wiley +1 more source
Hydrogen-bonding synthons in lamotrigine salts: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazin-2-ium 2-[(2-carboxyphenyl)disulfanyl]benzoate in its monohydrate and anhydrous forms [PDF]
Lamotrigine is a drug used in the treatment of epilepsy and related convulsive diseases. The drug in its free form is rather inadequate for pharmacological use due to poor absorption by the patient, which limits its bioavailability.
Baggio, Ricardo Fortunato +2 more
core +1 more source
Stimuli‐Responsive Afterglow from Luminescent Liquid Crystal Elastomers
An active glow luminescent system for encoding, signaling, and tracking in dark environments has been developed by integrating inorganic ultralong afterglow phosphors with adaptive liquid crystal elastomer actuators. Abstract Stimuli‐responsive luminescent polymeric materials which combine afterglow emission with mechanical flexibility and adaptability
Lansong Yue +2 more
wiley +1 more source
Intramolecular bridge‐locking frustrates detrimental anti‐parallel packing in evaporated organic films. This design enhances net polar orientation, leading to a twofold off‐resonance increase in the second‐order nonlinear susceptibility (χ(2)) without electric‐field poling.
Pierre‐Luc Thériault +6 more
wiley +1 more source
This review highlights the powerful synergy between mechanochemistry and solid reagents to replace hazardous substances traditionally used in organic synthesis. Such an approach offers a safer and more sustainable pathway for conducting organic reactions, with potential benefits in both reactivity and selectivity. The use of solid bases, acids, and gas
Adrien Gallego +4 more
wiley +1 more source

