Results 81 to 90 of about 296,249 (293)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Epigraphic Programs in Almoravid Constructions: The Commemoration of The Emirs’ Supremacy [PDF]
, 2018 Despite the ideas transmitted in the traditional historiography, during the Almoravid period, the arts –especially the architecture- had a prominent place within the issues of the Empire.
Marcos Cobaleda, María
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
But Maybe Everything That Dies Someday Comes Back [PDF]
, 2018 Book review: The death of treaty supremacy: an invisible constitutional change. By David L. Sloss. New York: Oxford University Press, 2016. Pp. xiv + 472.
Flaherty, Martin S.
core +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Constitutional Supremacy: National Constitutions vs. European Law
Australian and New Zealand Journal of European Studies, 2011 CESAA 18TH ANNUAL EUROPE ESSAY COMPETITION 2010 - Postgraduate winner: Vanessa McGlynn, University of New South Wales Almost 50 years after the European Court of Justice clearly established the supremacy of Community law, the question regarding the ...
Vanessa McGlynn
doaj +1 more source
How Overfishing Impacts You: The Battle for Ocean Supremacy: The Jellyfish Conquests 1 [PDF]
, 2011 This briefing published by OCEAN2012 exposes how overfishing impacts on the quality of fish people in Europe are eating. It is part of a series of briefings illustrating the impacts of overfishing on people or marine ecosystems caused by the excess ...
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
SUPREMACY OF THE CONSTITUTION THEORETICAL AND PRACTICAL CONSIDERATIONS [PDF]
Challenges of the Knowledge Society, 2018 Regarding the term of supremacy of the constitution, many authors consider that it is notorious and therefore does not require a special scientific analysis.
Marius ANDREESCU, Claudia ANDREESCU
doaj