Results 141 to 150 of about 55,425 (314)

Sociología Global: Hacia un Paradigma Alternativo desde el Sur

, 2023
Ronaldo Munck
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Leadership et volonté politique : deux éléments essentiels à la lutte contre la tuberculose au Canada. [PDF]

CMAJ
Bedingfield N, Tcholakov Y, Heffernan C.
europepmc   +1 more source

Soberanía de Datos Indígenas: Una Perspectiva Sociotécnica desde el Sur Global

Milia, Matías, FIGUEROA RODRIGUEZ, OSCAR LUIS, materechera, simeon, Tu, Yun-Pu, Zarate Vasquez, Julio Sebastian, Chung, Pyrou, Flores, Nkwi, Maditsi, Mothusiotsile Edwin, NWACHUKWU, UZOAMAKA   +8 more
openalex   +1 more source

Transformaciones del poder nacional en el Sur Global: un análisis desde el World Power Index (1992-2022) [PDF]

Daniel Morales Ruvalcaba
openalex   +1 more source

Mapeo de la Injusticia del Agua en Brasil: Una herramienta fundamental para la toma de decisiones en el Sur Global con respecto al agua subterránea [PDF]

, 2019
José Irivaldo Alves Oliveira Silva, José Rubens Morato Leite   +1 more
openalex   +1 more source

Analíticas de aprendizaje para el sur global

, 2018
El uso cada vez mayor de la tecnología en el ámbito de la educación ha dado lugar a una recopilación de datos sin precedentes sobre diversos aspectos del aprendizaje, la enseñanza y los sistemas educativos. Para hacer frente a los acuciantes desafíos, sectores de la educación de todo el mundo han reconocido el potencial que entraña analizar tales datos
Gasevic, Dragan, Prinsloo, Paul, Chen, Bodong, Fan, Yizhou, Rodrigo, Ma. Mercedes, Cobo, Cristóbal, Aguerrebere, Cecilia   +6 more
openaire   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Evaluation of a collaborative care system in primary care in the implementation of ambulatory follow-up in mental health: A study protocol. [PDF]

PLoS One
Dias Alves M, Jobic A, Rosso N, Abello M, Autret A, Vion-Dury J, Belzeaux R, Korrichi F.   +7 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source