From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
[Interdependent islands: health policies and medical practices in the care, management, and research of a neglected disease in the Global South]. [PDF]
Cad Saude PublicaSilveti L, Pereira AMM.
europepmc +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
[Excess mortality in winter in Argentina from 1997 to 2017: an approach based on public health and an epistemic dispute from the Global South]. [PDF]
Cad Saude PublicaAlmeida V, Alazraqui M.
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The association between scapular orientation and spinopelvic parameters. [PDF]
J Shoulder Elb ArthroplastEl Abiad R +10 more
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Le caractère changeant ce la race en contexte migratoire: « À Montréal je ne suis pas considérée comme une personne blanche. Au Brésil, oui. ». [PDF]
Can Rev SociolSousa BA, Chamberland L.
europepmc +1 more source
Analíticas de aprendizaje para el sur global
, 2018 El uso cada vez mayor de la tecnología en el ámbito de la educación ha dado lugar a una recopilación de datos sin precedentes sobre diversos aspectos del aprendizaje, la enseñanza y los sistemas educativos. Para hacer frente a los acuciantes desafíos, sectores de la educación de todo el mundo han reconocido el potencial que entraña analizar tales datos
Gasevic, Dragan +6 more
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source