Results 111 to 120 of about 56,017 (267)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Transición Geopolítica Global: Conectividad, Competición y Fragmentación. Introducción [PDF]

Revista UNISCI
Este número especial de la Revista UNISCI se centra en una de las cuestiones relevantes de la transformación que está aconteciendo en el sistema internacional, la transformación geopolítica y la rivalidad creciente entre Estados.
Soledad Segoviano, Antonio Marquina
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Corea del Sur en el contexto global

Con el objetivo de analizar a Corea del Sur en el contexto global del siglo xxi, se desarrolla una investigación colectiva de tipo proyectivo, de gran valor para investigadores y público en general con interés en los estudios coreanos en disciplinas de economía, relaciones internacionales y antropología.
Bárbara Inés Bavoleo, Matías Benítez, Karla Noemí Padilla Martínez, Myunghoon Baek, Víctor Manuel González Bernal, María del Carmen Hernández Cueto, Juan Felipe López Aymes, Juliana Correa Jaramillo, Silvia Seligson, Mercedes Susana Giuffre, Ángel Licona Michel, Sadcidi Zerpa de Hurtado   +11 more
openaire   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

BRICS: apuntes e interrogantes desde el desorden global

Cuadernos de Política Exterior Argentina
La irrupción y relevancia actual de los BRICS derivada de la crisis de la hegemonía estadounidense y el debilitamiento del internacionalismo liberal posterior a la Segunda Guerra Mundial, se presenta como un potencial cambio en la dinámica del poder ...
Santiago Molfino
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Reformar el orden global desde el Sur: los BRICS, multipolaridad y cooperación Sur-Sur

La declaración de los líderes del BRICS, emitida en julio de 2025 en Río de Janeiro, señala un momento clave en los esfuerzos del Sur Global por reconfigurar el orden internacional. En un contexto de conflictos armados y crisis sistémicas, el bloque propone reformas profundas a instituciones globales.
openaire   +2 more sources