Results 61 to 70 of about 55,425 (314)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Cocinar y comer en clave decolonial (Editorial)
SosQuua Revista Especializada en GastronomíaQuisiera iniciar esta presentación partiendo del siguiente cuestionamiento ¿qué es lo colonial y por ende su contra mirada, lo decolonial, la decolonialidad?
Rebeca Osorio González
doaj +1 more source
Réflexions sur l’histoire globale et transnationale
Cahiers d’histoire. Revue d’histoire critique, 2013 Akira Iriye, qui a dirigé avec Pierre-Yves Saunier le Palgrave Dictionary of Transnational History, paru en 2009, retrace comment, au fil du XXe siècle et particulièrement depuis les années 1990, la communauté historienne s’est de plus en plus intéressée au phénomène de la mondialisation et à l’histoire globale et transnationale.
openaire +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Estudios Demográficos y UrbanosEstudios previos en países del Norte Global han documentado un descenso de los movimientos internos de población durante la pandemia de COVID-19, acompañado de un aumento de los desplazamientos desde las grandes ciudades hacia áreas menos densamente ...
Miguel González-Leonardo +4 more
doaj +1 more source
Tram[p]as de la comunicación y la cultura, 2018 En el presente trabajo la autora plantea la necesidad de construir pensamiento alternativo de manera urgente e insurgente. Las epistemologías del sur, propone, podrían constituirse en alteridades permanentes y, al mismo tiempo, volverse vitales para cualquier lucha emancipatoria en la medida en la que se permita innovar en sus lógicas de producción ...
openaire +3 more sources