Results 91 to 100 of about 19,726 (265)

The problems of undifferentiated autoinflammatory diseases

Научно-практическая ревматология
Despite the progress of molecular genetic testing, the diagnostic issues of monogenic autoinflammatory diseases (AIDs) remain largely unresolved. It’s associated with a heterogeneous clinical picture and problems in interpreting the results of molecular ...
E. L. Nasonov, M. F. Beketova, S. O. Salugina, E. S. Fedorov, E. Yu. Zakharova, A. M. Lila   +5 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Biomechanical Perspectives on Surfing Performance: A Scoping Review

Biomechanics
Background/Objectives: Biomechanical research in surfing provides important insights into performance optimization and injury prevention, but the evidence remains fragmented across multiple domains.
Maria J. Van Der Sandt, Marta L. Machado, Catarina C. Santos, Mário J. Costa   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Análise antropométrica e dietética de surfistas amadores

Revista Brasileira de Nutrição Esportiva, 2018
O Surf é um esporte popular no Brasil, porém dados referentes à antropometria e dietéticos nos surfistas brasileiros ainda são limitados. Sendo assim, o objetivo da presente pesquisa foi verificar as características antropométricas e nutricionais de ...
Marcelo Romanovitch Ribas, Neslon Wasch Junior, Caio Henrique Amorim, Felipe dos Santos Cavalherio, Thais Almeida Góis dos Santos Teixeira, Julio César Bassan   +5 more
doaj  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Les nouveaux territoires du surf dans la ville

Téoros, 2009
La culture surf qui a tant marqué la côte ouest américaine à partir des années 1950, culture qui s’est mondialisée et commercialisée avec plusieurs tendances toutes aussi variées et inusitées les unes que les autres, a créé un univers aux proportions ...
Sylvain Lefebvre, Romain Roult
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source